Nizatidine CAS: 76963-41-2
MF: C12H21N5O2S2
MW: 331.46
An inhibitor of gastric acid secretion.

Nizatidine (CAS 76963-41-2)

Nizatidine | CAS 76963-41-2 is rated 5.0 out of 5 by 1.
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Alternate Names: N-[2-[[[2-[(Dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N′-methyl-2-nitro-1,1-ethenediamine
Application: Nizatidine is an inhibitor of gastric acid secretion
CAS Number: 76963-41-2
Purity: ≥98%
Molecular Weight: 331.46
Molecular Formula: C12H21N5O2S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Nizatidine is a histamine H2 receptor antagonist which functions as a potent inhibitor of gastric acid secretion.


References

1. Lin, T M., et al., 1986. Actions of nizatidine, a selective histamine H2-receptor antagonist, on gastric acid secretion in dogs, rats and frogs. The Journal of pharmacology and experimental therapeutics. 239(2): 406-10. PMID: 2877081
2. Abdel-Rahman, Susan M., et al., 2004. Developmental pharmacokinetics and pharmacodynamics of nizatidine. Journal of pediatric gastroenterology and nutrition. 38(4): 442-51. PMID: 15085026

Appearance :
Crystalline powder
Physical State :
Solid
Solubility :
Soluble in chloroform
Storage :
Store at room temperature
Melting Point :
132° C
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
PubChem CID :
3033637
SMILES :
CN\\C(NCCSCC1=CSC(CN(C)C)=N1)=C/[N+]([O-])=O

Download SDS (MSDS)

Certificate of Analysis

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What is the appearance of the compound?

Asked by: two2igm05
Thank you for your question. Nizatidine, sc-205771, is in white to off-white crystalline powder form.
Answered by: Chemical Support 4
Date published: 2017-05-19
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Rated 5 out of 5 by from Lin et al Lin et al. (PubMed ID 2877081) found that the histamine H2 receptor antagonist, Nizatidine, potently inhibited gastric acid secretion. -SCBT Publication Review
Date published: 2015-02-14
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