Molecular structure of Ranitidine, CAS Number: 66357-35-5
Ranitidine (CAS 66357-35-5)
Alternate Names:
N-[2-[[[5-[(Dimethylamino)methyl]-2 -furanyl]methyl]thio]ethyl]-N′-methyl-2-nitro-1,1-ethanediamine
Application:
Ranitidine is a selective and competitive histamine H2 receptor inhibitor
CAS Number:
66357-35-5
Purity:
≥95%
Molecular Weight:
314.41
Molecular Formula:
C13H22N4O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Ranitidine is a compound used in scientific research to study the regulation of gastric acid secretion. It acts as an antagonist of the histamine H2 receptor, which plays a significant role in controlling acid release in the stomach. In laboratory applications, ranitidine is used to understand the mechanisms of acid inhibition and the signal transduction pathways involved in gastric acid regulation. It also serves as a tool in research focused on the role of histamine in various physiological processes beyond acid secretion. Additionally, ranitidine is used in comparative studies with other H2 receptor antagonists to elucidate differences in potency, receptor binding affinity, and duration of action.
Ranitidine (CAS 66357-35-5) References
- The drug interaction potential of ranitidine: an update. | Klotz, U. and Kroemer, HK. 1991. Pharmacol Ther. 50: 233-44. PMID: 1763135
- Ranitidine. An updated review of its pharmacodynamic and pharmacokinetic properties and therapeutic use in peptic ulcer disease and other allied diseases. | Grant, SM., et al. 1989. Drugs. 37: 801-70. PMID: 2667937
- Ranitidine-induced chest pain. | Shimp, LA., et al. 1989. DICP. 23: 224-6. PMID: 2718500
- Ranitidine versus cimetidine. A comparison of their potential to cause clinically important drug interactions. | Smith, SR. and Kendall, MJ. 1988. Clin Pharmacokinet. 15: 44-56. PMID: 3042245
- Medicine and Media: The Ranitidine Debate. | Wagner, JA. and Colombo, JM. 2020. Clin Transl Sci. 13: 649-651. PMID: 32107850
- Ranitidine in the newborn. | Rosenthal, M. and Miller, PW. 1988. Arch Dis Child. 63: 88-9. PMID: 3258146
- Design and Synthesis of Ranitidine Analogs as Multi-Target Directed Ligands for the Treatment of Alzheimer's Disease. | Gao, J., et al. 2021. Int J Mol Sci. 22: PMID: 33803769
- Ranitidine and Risk of N-Nitrosodimethylamine (NDMA) Formation. | White, CM. and Hernandez, AV. 2021. JAMA. 326: 225-227. PMID: 34180953
- Risk of N-Nitrosodimethylamine (NMDA) Formation With Ranitidine. | Strauss, DG., et al. 2021. JAMA. 326: 2077. PMID: 34812875
- Ranitidine decreases human sperm motility and vitality and increases the activity of seminal creatine kinase. | Banihani, SA. and Al-Natsheh, AJ. 2022. Andrologia. 54: e14436. PMID: 35420703
- Ranitidine-associated hallucinations. | Price, W., et al. 1985. Eur J Clin Pharmacol. 29: 375-6. PMID: 4076334
- Interactions and non-interactions with ranitidine. | Kirch, W., et al. 1984. Clin Pharmacokinet. 9: 493-510. PMID: 6096071
- Clinical pharmacokinetics of ranitidine. | Roberts, CJ. 1984. Clin Pharmacokinet. 9: 211-21. PMID: 6329583
- Safety profile of ranitidine. A review. | Wormsley, KG. 1993. Drugs. 46: 976-85. PMID: 7510614
Inhibitor of:
ADHβ, ALDH2, BOCT, BPIL1, CYP20A1, Cyp2c66, Cyp2c69, CYP2D12, CYP2D40, Cyp3a44, Cyp3a57, Cyp3a59, Gastrin, Gastrokine 3, GIF, Gm14139, H2-Adβ, H2-I, H2RSP, HDC, Histamine, Histamine H2 Receptor, HNMT, HRT2, KA2, MATE1, MrgB2, Oct-2, Olfr251, Olfr376, Olfr667, Olfr822, Olfr827, Olfr944, Olr193, Pepsin A, Pepsin A3, Pepsin A4, Pepsin C, Pepsinogen A, SLC22A15, SLC22A24, and Vmn2r40.Activator of:
CCK, FMO1, FMO2, Intelectin-2, Mast Cell Protease 4, OCTN1, ORCTL2, Slc22a22, and SLC25A21.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Ranitidine, 1 g | sc-203679 | 1 g | $189.00 |