CCDC36 Activators
CCDC36 activators encompass a class of chemical compounds specifically designed to modulate the activity of the Coiled-Coil Domain Containing 36 (CCDC36) protein. CCDC36 is part of a broader family of proteins characterized by the presence of coiled-coil domains, which are structural motifs involved in facilitating protein-protein interactions. These domains are integral to a wide array of biological functions, including the assembly of protein complexes, cellular signaling, and intracellular trafficking. The precise biological role of CCDC36 remains an area of ongoing research, with early studies suggesting potential involvement in cellular processes related to the cytoskeleton and intracellular transport. Activators of CCDC36 are aimed at enhancing the functional activity of this protein, potentially shedding light on its role within the cell. The chemical structures of these activators can vary, ranging from small molecule compounds to larger biomolecules, each designed or identified for their ability to interact specifically with CCDC36, thereby modulating its activity or stability within the cellular environment.
The study of CCDC36 activators involves a multidisciplinary approach, incorporating techniques from molecular biology, biochemistry, and cell biology to elucidate their mechanism of action and the subsequent cellular consequences. Researchers delve into the interactions between CCDC36 and its activators, investigating how these compounds influence CCDC36's structure, localization, and interaction with other cellular components. Techniques such as fluorescence microscopy, co-immunoprecipitation, and pull-down assays are commonly used to study these interactions at a molecular level. Additionally, functional assays, including cell motility and cytoskeletal organization studies, may be employed to assess the impact of CCDC36 activation on cellular dynamics. Through these investigations, scientists aim to uncover the functional significance of CCDC36 in cellular processes, contributing to a broader understanding of the role of coiled-coil domain-containing proteins in cell biology and the complex network of protein interactions that underpin cellular function and organization.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits histone deacetylase, thereby potentially increasing transcription by allowing a more open chromatin state. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
Acts as a DNA methyltransferase inhibitor, potentially leading to the demethylation and activation of gene promoters. | ||||||
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
A metabolite of vitamin A that can bind to retinoic acid receptors and influence gene transcription. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Activates adenylyl cyclase, raising cAMP levels and potentially influencing gene expression through the PKA pathway. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Activates protein kinase C, which can lead to altered transcription factor activity and gene expression. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $30.00 $46.00 $82.00 $218.00 | 19 | |
A short-chain fatty acid that inhibits histone deacetylases, potentially affecting gene expression through epigenetic mechanisms. | ||||||
β-Estradiol | 50-28-2 | sc-204431 sc-204431A | 500 mg 5 g | $62.00 $178.00 | 8 | |
A form of estrogen that binds to estrogen receptors and can modulate gene expression. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
A synthetic glucocorticoid that can activate glucocorticoid receptors, influencing the transcription of target genes. | ||||||
Dimethyl Sulfoxide (DMSO) | 67-68-5 | sc-202581 sc-202581A sc-202581B | 100 ml 500 ml 4 L | $30.00 $115.00 $900.00 | 136 | |
Used as a solvent, which at high concentrations can influence gene expression and cellular differentiation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
An isoflavone found in soy that has been shown to modulate gene expression through its action as a tyrosine kinase inhibitor. | ||||||