CCDC36 Antibody (B-11): sc-514329
- CCDC36 Antibody (B-11) is a mouse monoclonal IgG1 λ CCDC36 antibody provided at 200 µg/ml
- raised against amino acids 125-424 mapping within an internal region of CCDC36 of human origin
- CCDC36 Antibody (B-11) is recommended for detection of CCDC36 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CCDC36 Antibody (B-11) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgGλ BP-HRP (mouse IgGλ binding protein-HRP) is the preferred secondary detection reagent for CCDC36 Antibody (B-11) for WB applications. This reagent is now offered in a bundle with CCDC36 Antibody (B-11) (see ordering information below). For additional m-IgGλ BP conjugates see our complete list of Mouse IgG Binding Proteins.
CCDC36 Antibody (B-11) is a mouse monoclonal IgG1 antibody that detects CCDC36 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CCDC36 (B-11) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CCDC36, also known as coiled-coil domain-containing protein 36 or cancer/testis antigen 74, is a 584 amino acid protein characterized by the presence of coiled-coil domains, which are crucial for mediating protein-protein interactions. These interactions are essential for various cellular processes, including the regulation of gene expression and the assembly of protein complexes involved in cellular signaling pathways. The gene encoding CCDC36 is located on human chromosome 3, a region that is significant not only for its high gene density but also for its association with several genetic disorders and cancer-related genes. Notably, chromosome 3 harbors key tumor suppressor genes, such as RASSF1, which plays a role in apoptosis, and SEMA3B, which is involved in angiogenesis regulation. Understanding the function and interactions of CCDC36 is vital, as it may provide insights into its role in cancer biology and potential therapeutic targets.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CCDC36 Antibody (B-11) References:
- Molecular cytogenetic dissection of human chromosomes 3 and 21 evolution. | Müller, S., et al. 2000. Proc Natl Acad Sci U S A. 97: 206-11. PMID: 10618396
- [New tumor suppressor genes in hot spots of human chromosome 3: new methods of identification]. | Braga, EA., et al. 2003. Mol Biol (Mosk). 37: 194-211. PMID: 12723467
- Plasticity of human chromosome 3 during primate evolution. | Tsend-Ayush, E., et al. 2004. Genomics. 83: 193-202. PMID: 14706448
- Genomic structure and paralogous regions of the inversion breakpoint occurring between human chromosome 3p12.3 and orangutan chromosome 2. | Yue, Y., et al. 2005. Cytogenet Genome Res. 108: 98-105. PMID: 15545721
- Comparative cytogenetics of human chromosome 3q21.3 reveals a hot spot for ectopic recombination in hominoid evolution. | Yue, Y., et al. 2005. Genomics. 85: 36-47. PMID: 15607420
- Evolutionarily plastic regions at human 3p21.3 coincide with tumor breakpoints identified by the 'elimination test'. | Darai, E., et al. 2005. Genomics. 86: 1-12. PMID: 15913951
- The DNA sequence, annotation and analysis of human chromosome 3. | Muzny, DM., et al. 2006. Nature. 440: 1194-8. PMID: 16641997
- Establishment and characterization of two uveal melanoma cell lines derived from tumors with loss of one chromosome 3. | Nareyeck, G., et al. 2006. Exp Eye Res. 83: 858-64. PMID: 16750193
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CCDC36 Antibody (B-11) | sc-514329 | 200 µg/ml | $316.00 | |||
CCDC36 Antibody (B-11): m-IgGλ BP-HRP Bundle | sc-524689 | 200 µg Ab, 40 µg BP | $354.00 | |||
CCDC36 Antibody (B-11) AC | sc-514329 AC | 500 µg/ml, 25% agarose | $416.00 | |||
CCDC36 Antibody (B-11) HRP | sc-514329 HRP | 200 µg/ml | $316.00 | |||
CCDC36 Antibody (B-11) FITC | sc-514329 FITC | 200 µg/ml | $330.00 | |||
CCDC36 Antibody (B-11) PE | sc-514329 PE | 200 µg/ml | $343.00 | |||
CCDC36 Antibody (B-11) Alexa Fluor® 488 | sc-514329 AF488 | 200 µg/ml | $357.00 | |||
CCDC36 Antibody (B-11) Alexa Fluor® 546 | sc-514329 AF546 | 200 µg/ml | $357.00 | |||
CCDC36 Antibody (B-11) Alexa Fluor® 594 | sc-514329 AF594 | 200 µg/ml | $357.00 | |||
CCDC36 Antibody (B-11) Alexa Fluor® 647 | sc-514329 AF647 | 200 µg/ml | $357.00 | |||
CCDC36 Antibody (B-11) Alexa Fluor® 680 | sc-514329 AF680 | 200 µg/ml | $357.00 | |||
CCDC36 Antibody (B-11) Alexa Fluor® 790 | sc-514329 AF790 | 200 µg/ml | $357.00 |