CCDC101 Activators
SAGA Complex Associated Factor 29 (SGF29), encoded by the SGF29 gene in humans, is a component of the Spt-Ada-Gcn5 acetyltransferase (SAGA) complex. The SAGA complex is a multisubunit protein complex involved in transcriptional regulation, particularly in processes such as transcription initiation, elongation, and histone modification.
SGF29 contributes to the functions of the SAGA complex via its ability to bind to specific histone modifications. It contains two chromatin reader domains: a C-terminal tandem tudor domain and a plant homeodomain (PHD). These domains allow SGF29 to bind to histones that have been marked by methylation, a type of chemical modification that affects gene expression.By reading these histone marks, SGF29 helps the SAGA complex to target specific genes for transcriptional regulation. This is a crucial aspect of gene expression and cellular function, affecting various biological processes such as cell growth, differentiation, and response to environmental changes.Mutations or dysregulation of the SAGA complex and its components, including SGF29, can lead to abnormal gene expression and have been implicated in various diseases. For instance, components of the SAGA complex have been linked to cancer, neurodevelopmental disorders, and other conditions.In summary, SGF29 is a vital part of the SAGA complex, involved in transcriptional regulation through its ability to read specific histone modifications.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Anacardic Acid | 16611-84-0 | sc-202463 sc-202463A | 5 mg 25 mg | $102.00 $204.00 | 13 | |
Activators of histone acetyltransferases could indirectly influence SGF29's role in transcriptional regulation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
These inhibitors change DNA methylation patterns, which could indirectly influence SGF29 activity in gene regulation. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibitors of the PI3K/Akt pathway might impact cellular processes and signaling pathways involving SGF29. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitors can affect gene expression and protein synthesis, potentially intersecting with SGF29 functions. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
Proteasome inhibitors can affect protein degradation pathways, potentially impacting the turnover of proteins within the SAGA complex, including SGF29. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
BET inhibitors affect transcription regulation and might indirectly influence SGF29's function in chromatin remodeling. | ||||||
Geldanamycin | 30562-34-6 | sc-200617B sc-200617C sc-200617 sc-200617A | 100 µg 500 µg 1 mg 5 mg | $39.00 $59.00 $104.00 $206.00 | 8 | |
HSP90 inhibitors can disrupt protein folding and function, potentially affecting components of the SAGA complex. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $79.00 | 2 | |
Activators of AMP-activated protein kinase can influence energy metabolism and transcriptional regulation, potentially impacting SGF29. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Sirtuin activators, influencing metabolic pathways and gene expression, may indirectly affect SGF29 function. | ||||||