CCDC101 Antibody (D-1): sc-515286
- CCDC101 Antibody (D-1) is a mouse monoclonal IgG1 κ CCDC101 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 40-59 within an internal region of CCDC101 of human origin
- CCDC101 Antibody (D-1) is recommended for detection of CCDC101 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-CCDC101 Antibody (D-1) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP and m-IgG1 BP-HRP are the preferred secondary detection reagents for CCDC101 Antibody (D-1) for WB applications. These reagents are now offered in bundles with CCDC101 Antibody (D-1) (see ordering information below).
CCDC101 Antibody (D-1) is a mouse monoclonal IgG1 kappa light chain antibody that detects CCDC101 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). CCDC101 Antibody (D-1) is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. CCDC101, also known as SGF29 (SAGA-associated factor 29) or STAF36, is a 293 amino acid nuclear protein that plays a crucial role in transcriptional regulation as a subunit of two histone acetyltransferase complexes: the TFTC (TATA-binding protein-free TAF-containing) and STAGA (SPT3-TAF9-GCN5/PCAF acetylase) complexes. CCDC101 modulates gene expression through histone acetylation, a key process in regulating chromatin structure and function, which ultimately influences cellular processes such as differentiation, proliferation, and response to environmental signals. Encoded by a gene located on human chromosome 16p11.2, CCDC101 is part of a genomic region associated with various disorders, including giant axonal neuropathy and Rubinstein-Taybi syndrome, highlighting CCDC101′s potential significance in both normal physiology and disease states.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
CCDC101 Antibody (D-1) References:
- The gene encoding gigaxonin, a new member of the cytoskeletal BTB/kelch repeat family, is mutated in giant axonal neuropathy. | Bomont, P., et al. 2000. Nat Genet. 26: 370-4. PMID: 11062483
- Genetics of inflammatory bowel disease: progress and prospects. | Mathew, CG. and Lewis, CM. 2004. Hum Mol Genet. 13 Spec No 1: R161-8. PMID: 14764625
- Advances in the genetics of inflammatory bowel disease. | Cho, JH. 2004. Curr Gastroenterol Rep. 6: 467-73. PMID: 15527676
- Deregulated expression of a novel component of TFTC/STAGA histone acetyltransferase complexes, rat SGF29, in hepatocellular carcinoma: possible implication for the oncogenic potential of c-Myc. | Kurabe, N., et al. 2007. Oncogene. 26: 5626-34. PMID: 17334388
- Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein. | Wang, YL., et al. 2008. J Biol Chem. 283: 33808-15. PMID: 18838386
- The Rubinstein-Taybi syndrome: occurrence in two sets of identical twins. | Baraitser, M. and Preece, MA. 1983. Clin Genet. 23: 318-20. PMID: 6682729
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CCDC101 Antibody (D-1) | sc-515286 | 200 µg/ml | $322.00 | |||
CCDC101 Antibody (D-1): m-IgG Fc BP-HRP Bundle | sc-528015 | 200 µg Ab; 10 µg BP | $361.00 | |||
CCDC101 Antibody (D-1): m-IgG1 BP-HRP Bundle | sc-533388 | 200 µg Ab; 20 µg BP | $361.00 | |||
CCDC101 Antibody (D-1) AC | sc-515286 AC | 500 µg/ml, 25% agarose | $424.00 | |||
CCDC101 Antibody (D-1) HRP | sc-515286 HRP | 200 µg/ml | $322.00 | |||
CCDC101 Antibody (D-1) FITC | sc-515286 FITC | 200 µg/ml | $336.00 | |||
CCDC101 Antibody (D-1) PE | sc-515286 PE | 200 µg/ml | $349.00 | |||
CCDC101 Antibody (D-1) Alexa Fluor® 488 | sc-515286 AF488 | 200 µg/ml | $364.00 | |||
CCDC101 Antibody (D-1) Alexa Fluor® 546 | sc-515286 AF546 | 200 µg/ml | $364.00 | |||
CCDC101 Antibody (D-1) Alexa Fluor® 594 | sc-515286 AF594 | 200 µg/ml | $364.00 | |||
CCDC101 Antibody (D-1) Alexa Fluor® 647 | sc-515286 AF647 | 200 µg/ml | $364.00 | |||
CCDC101 Antibody (D-1) Alexa Fluor® 680 | sc-515286 AF680 | 200 µg/ml | $364.00 | |||
CCDC101 Antibody (D-1) Alexa Fluor® 790 | sc-515286 AF790 | 200 µg/ml | $364.00 | |||
CCDC101 (D-1) Neutralizing Peptide | sc-515286 P | 100 µg/0.5 ml | $69.00 |