CAT Activators
Catalase (CAT) activators are chemical compounds that indirectly support the enhancement of CAT's enzymatic function, which is crucial for the reduction of oxidative stress in cells. Sodium Pyruvate and Melatonin extend the active life of CAT by scavenging hydrogen peroxide and reactive oxygen species, respectively, shielding CAT from oxidative inactivation and allowing it to function more efficiently. N-Acetylcysteine, through its role in glutathione synthesis, indirectly minimizes the substrate availability for CAT, thus lessening the enzyme's workload. Zinc Sulfate and Manganese(II) chloride serve to stabilize or modify the catalytic core of the enzyme, potentially increasing its activity. Furthermore, compounds like Silymarin and Ascorbic Acid protect CAT from oxidative damage or reduce its substrate concentration, thereby facilitating sustained catalytic action.
Compounds such as Curcumin and Resveratrol indirectly upregulate CAT activity by influencing transcription factors and sirtuins involved in the oxidative stress response, leading to an increase in CAT's presence and activity. Alpha-lipoic acid indirectly contributes to the catalase function by regenerating endogenous antioxidants, thereby conserving CAT's activity for its primary reaction with hydrogen peroxide. Similarly, Quercetin's modulation of stress response pathways can result in enhanced CAT activity.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Melatonin | 73-31-4 | sc-207848 sc-207848A sc-207848B sc-207848C sc-207848D sc-207848E | 1 g 5 g 25 g 100 g 250 g 1 kg | $65.00 $73.00 $218.00 $697.00 $1196.00 $3574.00 | 16 | |
Melatonin has been shown to protect catalase (CAT) activity under oxidative stress by scavenging reactive oxygen species and thus may indirectly enhance CAT activity by protecting it from oxidative damage. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $34.00 $74.00 $270.00 $114.00 | 34 | |
As a precursor to glutathione, N-Acetylcysteine contributes to the reduction of peroxide levels, indirectly supporting CAT activity by maintaining a lower level of its substrate, hydrogen peroxide. | ||||||
Zinc | 7440-66-6 | sc-213177 | 100 g | $48.00 | ||
Zinc ions can act as a cofactor for catalase (CAT), providing structural stability to the enzyme and potentially enhancing its activity. | ||||||
Manganese(II) chloride beads | 7773-01-5 | sc-252989 sc-252989A | 100 g 500 g | $19.00 $31.00 | ||
Manganese ions can replace iron in the heme group of catalase (CAT), altering its enzymatic activity. This can potentially enhance CAT activity under certain conditions where iron availability is limited. | ||||||
Silymarin group, mixture of isomers | 65666-07-1 | sc-301806 | 50 g | $325.00 | ||
Silymarin has antioxidant properties and can indirectly maintain the activity of catalase (CAT) by preventing oxidative damage to the enzyme. | ||||||
L-Ascorbic acid, free acid | 50-81-7 | sc-202686 | 100 g | $46.00 | 5 | |
Ascorbic Acid can reduce hydrogen peroxide and thus reduce the burden on catalase (CAT), indirectly maintaining its activity by keeping the substrate concentration optimal. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin has been shown to increase the expression of catalase (CAT) indirectly by modulating the Nrf2 pathway, which can lead to increased enzymatic activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol can increase the activity of catalase (CAT) indirectly through the activation of the SIRT1 pathway, which is known to regulate oxidative stress responses. | ||||||
α-Lipoic Acid | 1077-28-7 | sc-202032 sc-202032A sc-202032B sc-202032C sc-202032D | 5 g 10 g 250 g 500 g 1 kg | $69.00 $122.00 $212.00 $380.00 $716.00 | 3 | |
Alpha-lipoic acid can regenerate other antioxidants, thereby sparing catalase (CAT) and indirectly enhancing its activity through a reduced oxidative load. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin has been reported to increase the activity of CAT indirectly by modulating signaling pathways that respond to oxidative stress. | ||||||