Santa Cruz Biotechnology now offers a broad range of caspase-8 Activators. Caspase family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-8 Activators offered by Santa Cruz activate caspase-8 and, in some cases, other apoptosis and tumor related proteins. View detailed caspase-8 Activator specifications, including caspase-8 Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Mitomycin C | 50-07-7 | sc-3514A sc-3514 sc-3514B | 2 mg 5 mg 10 mg | $65.00 $99.00 $140.00 | 85 | |
Mitomycin C (CAS 50-07-7) is a naturally occurring antibiotic isolated from the bacterium Streptomyces caespitosus. As an activator of caspase-8, it induces apoptosis in cells by triggering the extrinsic apoptotic pathway. It forms DNA crosslinks that can cause DNA damage, subsequently leading to caspase-8 activation. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Induces apoptosis by activating caspase-8 through the mitochondrial pathway. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $214.00 $622.00 | 1 | |
Romidepsin (CAS 128517-07-7) is a potent activator of caspase-8, initiating apoptosis through the extrinsic pathway by inducing caspase-8 activation. | ||||||
Borrelidin | 7184-60-3 | sc-200379 sc-200379A | 100 µg 1 mg | $94.00 $225.00 | 2 | |
Borrelidin (CAS 7184-60-3) functions as a caspase-8 activator, instigating apoptosis via the extrinsic pathway by facilitating caspase-8 activation. This compound plays a role in cell death regulation. | ||||||
Alsterpaullone | 237430-03-4 | sc-202453 sc-202453A | 1 mg 5 mg | $67.00 $306.00 | 2 | |
Alsterpaullone (CAS 237430-03-4) acts as a caspase-8 activator, triggering apoptosis through the extrinsic pathway by facilitating caspase-8 activation. This compound is involved in the regulation of cell death processes. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $57.00 $182.00 $92.00 | 21 | |
Initiates DNA damage, leading to p53 activation and subsequent caspase-8 activation. | ||||||
DuP-697 | 88149-94-4 | sc-200680 sc-200680A | 5 mg 25 mg | $150.00 $500.00 | ||
DuP-697 (CAS 88149-94-4) functions as a caspase-8 activator, initiating apoptosis via the extrinsic pathway by facilitating caspase-8 activation. This compound plays a role in the regulation of cell death processes. | ||||||
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Causes DNA damage that leads to the activation of caspase-8 via the intrinsic pathway. | ||||||
Prodigiosin | 82-89-3 | sc-202298 sc-202298A | 500 µg 2.5 mg | $362.00 $1249.00 | 5 | |
Prodigiosin (CAS 82-89-3) serves as a caspase-8 activator, initiating apoptosis through the extrinsic pathway by facilitating caspase-8 activation. This compound contributes to the regulation of cell death processes within biological systems. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $115.00 $337.00 | 3 | |
Triggers the mitochondrial pathway, eventually leading to caspase-8 activation. | ||||||