Date published: 2025-11-22

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caspase-8 Activators

Santa Cruz Biotechnology now offers a broad range of caspase-8 Activators. Caspase family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-8 Activators offered by Santa Cruz activate caspase-8 and, in some cases, other apoptosis and tumor related proteins. View detailed caspase-8 Activator specifications, including caspase-8 Activator CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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Items 1 to 10 of 15 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Mitomycin C

50-07-7sc-3514A
sc-3514
sc-3514B
2 mg
5 mg
10 mg
$65.00
$99.00
$140.00
85
(5)

Mitomycin C (CAS 50-07-7) is a naturally occurring antibiotic isolated from the bacterium Streptomyces caespitosus. As an activator of caspase-8, it induces apoptosis in cells by triggering the extrinsic apoptotic pathway. It forms DNA crosslinks that can cause DNA damage, subsequently leading to caspase-8 activation.

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$150.00
$388.00
113
(4)

Induces apoptosis by activating caspase-8 through the mitochondrial pathway.

Romidepsin

128517-07-7sc-364603
sc-364603A
1 mg
5 mg
$214.00
$622.00
1
(1)

Romidepsin (CAS 128517-07-7) is a potent activator of caspase-8, initiating apoptosis through the extrinsic pathway by inducing caspase-8 activation.

Borrelidin

7184-60-3sc-200379
sc-200379A
100 µg
1 mg
$94.00
$225.00
2
(1)

Borrelidin (CAS 7184-60-3) functions as a caspase-8 activator, instigating apoptosis via the extrinsic pathway by facilitating caspase-8 activation. This compound plays a role in cell death regulation.

Alsterpaullone

237430-03-4sc-202453
sc-202453A
1 mg
5 mg
$67.00
$306.00
2
(1)

Alsterpaullone (CAS 237430-03-4) acts as a caspase-8 activator, triggering apoptosis through the extrinsic pathway by facilitating caspase-8 activation. This compound is involved in the regulation of cell death processes.

Camptothecin

7689-03-4sc-200871
sc-200871A
sc-200871B
50 mg
250 mg
100 mg
$57.00
$182.00
$92.00
21
(2)

Initiates DNA damage, leading to p53 activation and subsequent caspase-8 activation.

DuP-697

88149-94-4sc-200680
sc-200680A
5 mg
25 mg
$150.00
$500.00
(1)

DuP-697 (CAS 88149-94-4) functions as a caspase-8 activator, initiating apoptosis via the extrinsic pathway by facilitating caspase-8 activation. This compound plays a role in the regulation of cell death processes.

Etoposide (VP-16)

33419-42-0sc-3512B
sc-3512
sc-3512A
10 mg
100 mg
500 mg
$32.00
$170.00
$385.00
63
(1)

Causes DNA damage that leads to the activation of caspase-8 via the intrinsic pathway.

Prodigiosin

82-89-3sc-202298
sc-202298A
500 µg
2.5 mg
$362.00
$1249.00
5
(1)

Prodigiosin (CAS 82-89-3) serves as a caspase-8 activator, initiating apoptosis through the extrinsic pathway by facilitating caspase-8 activation. This compound contributes to the regulation of cell death processes within biological systems.

Betulinic Acid

472-15-1sc-200132
sc-200132A
25 mg
100 mg
$115.00
$337.00
3
(1)

Triggers the mitochondrial pathway, eventually leading to caspase-8 activation.