Santa Cruz Biotechnology now offers a broad range of caspase-5 Inhibitors. Caspase family members function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Caspase-5 Inhibitors offered by Santa Cruz inhibit caspase-5 and, in some cases, other apoptosis and tumor related proteins. View detailed caspase-5 Inhibitor specifications, including caspase-5 Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Caspase-1 Inhibitor IV | 154674-81-4 | sc-300324 | 1 mg | $188.00 | ||
Caspase-1 Inhibitor IV functions as a selective modulator of caspase-5, engaging in specific interactions that alter the enzyme's active site dynamics. Its unique binding affinity leads to a reduction in enzymatic turnover, characterized by a distinct competitive inhibition profile. This compound's ability to stabilize intermediate states may influence downstream signaling pathways, thereby affecting cellular responses to stress and inflammation through targeted protease regulation. | ||||||
VX-765 | 273404-37-8 | sc-475845 sc-475845A sc-475845B | 5 mg 10 mg 50 mg | $228.00 $302.00 $968.00 | 1 | |
Originally targeting caspase-1, it can affect caspase-5 due to structural similarities between these caspases. | ||||||
Z-WEHD-FMK | sc-3078 | 1 mg | $172.00 | 1 | ||
Z-WEHD-FMK is a potent inhibitor of caspase-5, characterized by its ability to form covalent bonds with the enzyme's active site. This irreversible binding alters the conformational landscape of caspase-5, effectively hindering its proteolytic activity. The compound's specificity is attributed to its unique peptide sequence, which mimics natural substrates, allowing for selective modulation of apoptotic pathways. Its kinetic profile reveals a slow-onset inhibition, providing prolonged effects on cellular signaling cascades. | ||||||
Emricasan | 254750-02-2 | sc-507387 | 5 mg | $90.00 | ||
A pan-caspase inhibitor, potentially reduces caspase-5 activity by inhibiting related caspases. | ||||||
PD 150606 | 179528-45-1 | sc-222133 sc-222133A | 5 mg 25 mg | $118.00 $403.00 | 18 | |
An inhibitor of calpain, indirectly affects caspase-5 by modulating calcium-mediated apoptotic pathways. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
A proteasome inhibitor that can indirectly influence caspase-5 activity through the regulation of protein degradation pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
A PI3K inhibitor, indirectly impacts caspase-5 by affecting the AKT pathway which is involved in apoptosis regulation. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
A p38 MAPK inhibitor, potentially affects caspase-5 by altering the stress response and inflammatory signaling pathways. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another PI3K inhibitor, it can indirectly affect caspase-5 activity through the AKT pathway. | ||||||
Apoptosis Activator VII, Apoptozole | 1054543-47-3 | sc-221257 | 10 mg | $243.00 | 1 | |
An inhibitor of HSP70, it can indirectly influence caspase-5 by modulating stress responses and protein folding pathways. | ||||||