Cardiotrophin-1 Inhibitors belong to a distinct chemical class designed to modulate the activity of cardiotrophin-1, a cytokine that plays a crucial role in various physiological processes, particularly within the cardiovascular system. Cardiotrophin-1 is a member of the interleukin-6 (IL-6) family of cytokines and is involved in the regulation of cell survival, growth, and differentiation. Within the intricate signaling networks governing cardiac function, cardiotrophin-1 has been identified as a key mediator of cardiomyocyte hypertrophy and inflammation. As a consequence, researchers have endeavored to develop specific inhibitors targeting the actions of cardiotrophin-1 to gain insights into its regulatory mechanisms and explore potential avenues for intervention in conditions characterized by aberrant cardiac remodeling.
Cardiotrophin-1 Inhibitors are meticulously engineered to selectively interfere with the signaling pathways activated by cardiotrophin-1, thereby influencing downstream cellular responses. These inhibitors typically interact with molecular targets involved in the cardiotrophin-1 signaling cascade, such as cell surface receptors and intracellular kinases, to modulate the transmission of signals and ultimately mitigate the effects of cardiotrophin-1. By unraveling the intricacies of cardiotrophin-1 signaling through the use of these inhibitors, researchers aim to expand our understanding of the molecular underpinnings of cardiovascular physiology and pathology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, a kinase which can be part of signaling pathways in which CTF1 may be involved. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A specific inhibitor of PI3K, which could modulate pathways affecting CTF1 function. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Targets AKT, potentially altering downstream effects of CTF1-related pathways. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor that can modulate cellular processes where CTF1 is implicated. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor, possibly affecting stress response pathways involving CTF1. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
Inhibits p38 MAPK, potentially modifying the activity of pathways linked to CTF1. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor, which can have an impact on cell growth and proliferation pathways with CTF1. | ||||||
Nutlin-3 | 548472-68-0 | sc-45061 sc-45061A sc-45061B | 1 mg 5 mg 25 mg | $56.00 $212.00 $764.00 | 24 | |
Disrupts p53-MDM2 interaction, potentially influencing pathways where CTF1 is a factor. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $132.00 $1064.00 | 115 | |
Proteasome inhibitor, could affect protein degradation processes that involve CTF1. | ||||||
Thalidomide | 50-35-1 | sc-201445 sc-201445A | 100 mg 500 mg | $109.00 $350.00 | 8 | |
Modulates ubiquitin ligase activity, potentially affecting CTF1 stability and function. | ||||||