Date published: 2025-11-25

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Cardiotrophin-1 Inhibitors

Cardiotrophin-1 Inhibitors belong to a distinct chemical class designed to modulate the activity of cardiotrophin-1, a cytokine that plays a crucial role in various physiological processes, particularly within the cardiovascular system. Cardiotrophin-1 is a member of the interleukin-6 (IL-6) family of cytokines and is involved in the regulation of cell survival, growth, and differentiation. Within the intricate signaling networks governing cardiac function, cardiotrophin-1 has been identified as a key mediator of cardiomyocyte hypertrophy and inflammation. As a consequence, researchers have endeavored to develop specific inhibitors targeting the actions of cardiotrophin-1 to gain insights into its regulatory mechanisms and explore potential avenues for intervention in conditions characterized by aberrant cardiac remodeling.

Cardiotrophin-1 Inhibitors are meticulously engineered to selectively interfere with the signaling pathways activated by cardiotrophin-1, thereby influencing downstream cellular responses. These inhibitors typically interact with molecular targets involved in the cardiotrophin-1 signaling cascade, such as cell surface receptors and intracellular kinases, to modulate the transmission of signals and ultimately mitigate the effects of cardiotrophin-1. By unraveling the intricacies of cardiotrophin-1 signaling through the use of these inhibitors, researchers aim to expand our understanding of the molecular underpinnings of cardiovascular physiology and pathology.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Inhibits PI3K, a kinase which can be part of signaling pathways in which CTF1 may be involved.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

A specific inhibitor of PI3K, which could modulate pathways affecting CTF1 function.

Triciribine

35943-35-2sc-200661
sc-200661A
1 mg
5 mg
$102.00
$138.00
14
(1)

Targets AKT, potentially altering downstream effects of CTF1-related pathways.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$39.00
$90.00
212
(2)

MEK inhibitor that can modulate cellular processes where CTF1 is implicated.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

JNK inhibitor, possibly affecting stress response pathways involving CTF1.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

Inhibits p38 MAPK, potentially modifying the activity of pathways linked to CTF1.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$62.00
$155.00
$320.00
233
(4)

mTOR inhibitor, which can have an impact on cell growth and proliferation pathways with CTF1.

Nutlin-3

548472-68-0sc-45061
sc-45061A
sc-45061B
1 mg
5 mg
25 mg
$56.00
$212.00
$764.00
24
(1)

Disrupts p53-MDM2 interaction, potentially influencing pathways where CTF1 is a factor.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$132.00
$1064.00
115
(2)

Proteasome inhibitor, could affect protein degradation processes that involve CTF1.

Thalidomide

50-35-1sc-201445
sc-201445A
100 mg
500 mg
$109.00
$350.00
8
(0)

Modulates ubiquitin ligase activity, potentially affecting CTF1 stability and function.