Calcium Probes

CalciFluor™ Fluo-8, AM is a specialized calcium indicator that exhibits remarkable fluorescence properties upon binding to calcium ions. Its unique design allows for rapid cellular uptake and subsequent release of the fluorophore, enabling real-time monitoring of calcium dynamics. The compound's high sensitivity to calcium fluctuations facilitates the detection of subtle changes in intracellular calcium levels, making it an effective tool for studying calcium signaling pathways. Its photostability ensures reliable imaging over extended periods, enhancing experimental accuracy.

Hydroxy naphthol blue disodium salt is a versatile chelating agent that selectively interacts with calcium ions, forming stable complexes that exhibit distinct colorimetric changes. This property allows for precise quantification of calcium concentrations in various environments. The compound's unique molecular structure enhances its binding affinity, facilitating rapid reaction kinetics. Its solubility in aqueous solutions further supports its role in dynamic calcium detection, making it a valuable tool in analytical chemistry.

FURA-PE3/AM is a fluorescent calcium indicator that exhibits unique spectral properties upon binding to calcium ions. Its design allows for ratiometric measurements, providing enhanced sensitivity and accuracy in detecting calcium fluctuations. The compound's ability to permeate cell membranes and its subsequent hydrolysis into an active form enable real-time monitoring of intracellular calcium dynamics. This responsiveness to calcium levels is crucial for studying cellular signaling pathways.

TPEN is a selective chelator that exhibits a high affinity for calcium ions, facilitating intricate interactions within biological systems. Its unique structure allows for the formation of stable complexes, influencing calcium homeostasis and signaling pathways. The compound's kinetic properties enable rapid binding and release of calcium, making it a valuable tool for probing calcium-mediated processes. Additionally, TPEN's solubility and stability enhance its effectiveness in various experimental conditions.

FLUO 3/AM is a fluorescent calcium indicator that exhibits remarkable sensitivity to calcium ion fluctuations. Its unique design allows for rapid cellular uptake and subsequent de-esterification, resulting in enhanced fluorescence upon calcium binding. This compound demonstrates distinct photophysical properties, enabling real-time visualization of calcium dynamics within live cells. The kinetics of its fluorescence response provide insights into calcium signaling events, making it a powerful tool for studying cellular processes.

Nuclear Fast Red is a synthetic dye that exhibits strong affinity for calcium ions, facilitating specific interactions that enhance its staining properties. Its unique structure allows for effective binding to calcium, leading to distinct colorimetric changes. The compound's reaction kinetics are characterized by rapid binding and release, enabling dynamic tracking of calcium levels. Additionally, its solubility in various solvents enhances its versatility in different experimental conditions, making it a valuable tool for visualizing calcium distribution.

CalciFluor™ Fluo-8H, AM is a fluorescent calcium indicator that exhibits high sensitivity to calcium ion fluctuations. Its unique design allows for rapid cellular uptake and subsequent de-esterification, resulting in enhanced fluorescence upon calcium binding. This compound demonstrates exceptional photostability and a broad excitation/emission spectrum, enabling precise monitoring of calcium dynamics in live cells. Its selective interaction with calcium ions facilitates real-time visualization of intracellular signaling pathways.

Coelenterazine 400 a is a bioluminescent compound that exhibits unique interactions with calcium ions, enhancing its luminescent properties upon binding. This compound undergoes specific conformational changes that facilitate energy transfer, resulting in a distinct emission profile. Its rapid kinetics allow for real-time monitoring of calcium fluctuations, making it an effective tool for studying dynamic cellular processes. The compound's stability and sensitivity to calcium levels enable detailed exploration of intracellular signaling mechanisms.

FURA-2 pentapotassium salt is a fluorescent calcium indicator that exhibits remarkable spectral properties upon calcium binding. Its unique ability to undergo a significant shift in fluorescence intensity allows for precise detection of calcium ion concentrations. The compound's dual-excitation wavelengths enable ratiometric measurements, enhancing accuracy in quantifying calcium dynamics. Additionally, its rapid response time facilitates the observation of transient calcium events, making it a powerful tool for investigating cellular signaling pathways.

BAPTA, Tetrasodium Salt is a highly selective chelator for calcium ions, exhibiting a strong affinity that enables it to effectively modulate calcium levels in various environments. Its unique structure allows for rapid binding and release of calcium, influencing reaction kinetics and cellular processes. The compound's ability to form stable complexes with calcium ions minimizes unwanted interactions, making it an essential tool for studying calcium-dependent mechanisms in biochemical research.