Calcium Channel Modulators
Items 21 to 30 of 167 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ranolazine Dihydrochloride | 95635-56-6 | sc-205834 sc-205834A | 100 mg 500 mg | $167.00 $615.00 | 1 | |
Ranolazine Dihydrochloride functions as a calcium channel modulator by engaging with specific binding sites on calcium channels, leading to altered ion permeability. Its unique structure facilitates distinct interactions with channel proteins, influencing their activation thresholds and inactivation kinetics. This compound exhibits a nuanced ability to stabilize intermediate states of the channel, thereby fine-tuning calcium flow and impacting downstream signaling pathways in a variety of cellular contexts. | ||||||
8-Bromo-cADP-Ribose (8-Br-cADPR) | 151898-26-9 | sc-201514 sc-201514B | 100 µg 1 mg | $133.00 $561.00 | 12 | |
8-Bromo-cADP-Ribose acts as a calcium channel modulator by selectively influencing intracellular calcium release mechanisms. Its unique ability to mimic cyclic ADP-ribose allows it to interact with ryanodine receptors, enhancing calcium mobilization from the endoplasmic reticulum. This compound exhibits rapid kinetics in modulating calcium signaling, promoting transient calcium spikes that can significantly alter cellular excitability and signaling cascades, thereby affecting various physiological processes. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
Nifedipine functions as a calcium channel modulator by selectively inhibiting L-type calcium channels, which are crucial for calcium influx in excitable tissues. Its unique structure allows for specific binding to the channel's pore, stabilizing it in an inactive state. This modulation results in a decrease in calcium entry, influencing downstream signaling pathways. The compound exhibits distinct reaction kinetics, characterized by a rapid onset of action and a relatively short duration of effect, impacting cellular calcium dynamics. | ||||||
Adenosine 5′-[γ-thio]triphosphate tetralithium salt | 93839-89-5 | sc-214500 sc-214500A sc-214500B | 1 mg 5 mg 10 mg | $82.00 $179.00 $308.00 | 1 | |
Adenosine 5'-[γ-thio]triphosphate tetralithium salt acts as a calcium channel modulator by enhancing the sensitivity of calcium channels to voltage changes. Its unique γ-thio substitution alters the binding affinity for channel proteins, promoting a conformational shift that facilitates calcium ion flow. This compound exhibits distinctive reaction kinetics, with a prolonged interaction time that influences calcium-dependent signaling cascades, ultimately affecting cellular excitability and function. | ||||||
LY 354740 | 176199-48-7 | sc-204064 sc-204064A | 10 mg 50 mg | $266.00 $886.00 | 2 | |
LY 354740 functions as a calcium channel modulator by selectively interacting with specific receptor sites, leading to altered calcium ion permeability. Its unique structural features enable it to stabilize channel conformations, enhancing calcium influx in response to depolarization. The compound exhibits distinct binding kinetics, characterized by a rapid association and slower dissociation, which fine-tunes calcium signaling pathways and influences cellular homeostasis. | ||||||
L-Tetrahydropalmatine | 483-14-7 | sc-202203 sc-202203A | 100 mg 500 mg | $214.00 $482.00 | 1 | |
L-Tetrahydropalmatine functions as a calcium channel modulator by selectively interacting with voltage-gated calcium channels, influencing their conformational states. This compound exhibits unique kinetic properties, allowing for rapid modulation of calcium influx in response to cellular stimuli. Its structural features enable it to stabilize channel openings, thereby fine-tuning calcium signaling pathways. The compound's distinct binding affinity contributes to its ability to regulate intracellular calcium homeostasis effectively. | ||||||
2′,4′-Dichlorobenzamil • HCl | 2088-58-6 | sc-200197 sc-200197A | 5 mg 25 mg | $81.00 $316.00 | 6 | |
2',4'-Dichlorobenzamil • HCl acts as a calcium channel modulator by selectively binding to specific sites on calcium channels, altering their gating mechanisms. This compound exhibits a unique ability to influence the kinetics of calcium ion flow, promoting a nuanced response to electrical stimuli. Its distinct molecular structure enhances its interaction with channel proteins, facilitating precise modulation of calcium-dependent processes within cells. | ||||||
Fendiline hydrochloride | 13636-18-5 | sc-239988 | 5 g | $119.00 | 3 | |
Fendiline hydrochloride functions as a calcium channel modulator by engaging with the voltage-gated calcium channels, leading to alterations in their conformational states. This compound exhibits a unique affinity for specific channel subtypes, influencing the rate of calcium ion influx. Its structural characteristics allow for effective stabilization of the inactivated state of the channels, thereby fine-tuning cellular excitability and calcium signaling pathways. | ||||||
Bepridil hydrochloride | 74764-40-2 | sc-202974 sc-202974A | 10 mg 25 mg | $52.00 $104.00 | 2 | |
Bepridil hydrochloride acts as a calcium channel modulator by selectively binding to the L-type calcium channels, promoting a distinct alteration in their gating kinetics. This compound exhibits a unique interaction profile, enhancing the stability of the channel's closed state while reducing calcium ion permeability. Its molecular structure facilitates specific hydrogen bonding interactions, which can influence channel dynamics and contribute to the modulation of intracellular calcium levels. | ||||||
Nimodipine-d7 | 1246815-36-0 | sc-219378 | 1 mg | $240.00 | ||
Nimodipine-d7 acts as a calcium channel modulator by selectively binding to L-type calcium channels, leading to a reduction in calcium ion influx. Its deuterated structure enhances stability and alters reaction kinetics, allowing for precise modulation of channel activity. This compound exhibits unique interactions that can influence the gating mechanisms of calcium channels, thereby affecting intracellular calcium dynamics and cellular signaling pathways. Its distinct isotopic labeling provides insights into metabolic pathways and channel behavior. | ||||||