2′,4′-Dichlorobenzamil • HCl (CAS 2088-58-6)
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2′,4′-Dichlorobenzamil • HCl is the hydrochloride salt preparation of 2′,4′-Dichlorobenzamil, an inhibitor of Na+/Ca2+ exchanger protein (NCX). Blockade of NCX by 2′,4′-Dichlorobenzamil was shown to inhibit the K+-induced suppression of endothelium-dependent relaxation and to suppress the correlated increase of intracellular Ca2+ concentrations. NCX blockade by 2′,4′-Dichlorobenzamil also abolishes histamine-induced Ca2+ oscillations. 2′,4′-Dichlorobenzamil is described to inhibit whole-cell inward currents stimulated by 8-Br-cGMP at nucleotide-gated cation channels. Caffeine-induced release of Ca2+ internal stores from olfactory receptor neurons and formation of a caffeine-induced current were blocked by 2′,4′-Dichlorobenzamil.
2′,4′-Dichlorobenzamil • HCl (CAS 2088-58-6) References
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Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
2′,4′-Dichlorobenzamil • HCl, 5 mg | sc-200197 | 5 mg | $81.00 | |||
2′,4′-Dichlorobenzamil • HCl, 25 mg | sc-200197A | 25 mg | $316.00 |