cadherin-7 Activators
Cadherin-7 activators are a specialized group of molecules that target and augment the function of cadherin-7, a member of the cadherin superfamily of calcium-dependent cell adhesion proteins. Cadherin-7 is known for its role in facilitating cell-cell adhesion and communication, contributing to the organization and maintenance of tissue structure. This particular type of cadherin is characterized by its extracellular domain, which mediates homophilic binding interactions with cadherin molecules on adjacent cells, and its intracellular domain, which connects to the cytoskeleton through catenins and other associated proteins. Cadherin-7 activators enhance this adhesive function, potentially by stabilizing the cadherin interactions at the cell surface or by promoting the cadherin-catenin complex formation, leading to a more robust cell-cell adhesion and improved cellular network integrity.
The investigation into cadherin-7 activators encompasses a detailed analysis of the protein's structure-function relationship, as well as the dynamic processes that regulate its activity at the cellular level. Scientists utilize a variety of biochemical assays to measure the adhesive properties of cadherin-7 in the presence of these activators, observing changes in cell aggregation, adhesion strength, and cadherin-mediated signaling pathways. Structural biology techniques, such as X-ray crystallography and nuclear magnetic resonance (NMR) spectroscopy, contribute to the understanding of how activators interact with the cadherin-7 molecule. These studies can reveal the binding sites for activators and demonstrate how such interactions lead to conformational changes that promote adhesion. Additionally, live-cell imaging and fluorescence microscopy provide real-time insights into how cadherin-7 activators affect the dynamics of cell adhesion and the cytoskeletal connections in living cells.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $65.00 $319.00 $575.00 $998.00 | 28 | |
Retinoic acid is known to regulate gene expression and cell differentiation. It may potentially induce cadherin-7 expression by promoting differentiation of cells where cadherin-7 is normally expressed. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin has been reported to modulate gene expression. Its antioxidant properties might potentially induce cadherin-7 expression in response to oxidative stress. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is thought to have gene modulation properties. It could potentially induce cadherin-7 expression by modulating signaling pathways involved in cell-to-cell adhesion. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, an isoflavone, can influence gene expression. It may potentially induce cadherin-7 expression by interacting with signaling pathways related to cell adhesion and tissue development. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
5-Azacytidine is a demethylating agent that can alter gene expression. It may potentially induce cadherin-7 expression by demethylating the cadherin-7 promoter region. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $76.00 $82.00 $367.00 | 36 | |
Dexamethasone, a glucocorticoid, can regulate gene expression. It may potentially induce cadherin-7 expression by affecting pathways related to cell adhesion and tissue development. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
(-)-Epigallocatechin Gallate can modulate gene expression. It might potentially induce cadherin-7 expression by counteracting oxidative stress and influencing cell adhesion pathways. | ||||||
Indole-3-carbinol | 700-06-1 | sc-202662 sc-202662A sc-202662B sc-202662C sc-202662D | 1 g 5 g 100 g 250 g 1 kg | $38.00 $60.00 $143.00 $306.00 $1012.00 | 5 | |
Indole-3-carbinol can impact gene expression. It may potentially induce cadherin-7 expression by interacting with pathways related to cell adhesion and tissue development. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
DL-Sulforaphane can influence gene expression. It might potentially induce cadherin-7 expression by modulating cellular stress response pathways. | ||||||
Folic Acid | 59-30-3 | sc-204758 | 10 g | $72.00 | 2 | |
Folic acid is essential for DNA synthesis and repair. It might potentially induce cadherin-7 expression by contributing to the maintenance of genomic stability. | ||||||