C8orf45 Activators
Minichromosome Maintenance Domain Containing 2 (MCMDC2) is a protein that, while not extensively characterized, is thought to be involved in the fundamental cellular process of DNA replication. It is part of the larger family of proteins known as minichromosome maintenance (MCM) proteins, which are essential for the initiation and elongation phases of DNA replication in eukaryotic cells.The classical MCM proteins, MCM2-7, form a hexameric complex that functions as a helicase, unwinding DNA at the replication fork to allow the synthesis of new DNA strands. MCMDC2, by virtue of its name and domain structure, is likely associated with this family and may play a role in the regulation of DNA replication, although its exact function within the MCM complex or its possible role outside the complex is not well established.
The MCM family is highly conserved across eukaryotes, underscoring its importance in cellular division and the maintenance of genomic stability. Disruption of MCM function is known to result in replication stress, which can lead to genomic instability-a hallmark of many cancers. MCMDC2, therefore, might be of particular interest in the study of cell cycle regulation and oncogenesis.MCMDC2 may also interact with other proteins involved in replication, such as CDC6 and CDT1, which are responsible for loading the MCM complex onto DNA. It could potentially act as a regulatory subunit or have a scaffolding function that influences the assembly or activity of the replication machinery.
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Items 1 to 10 of 12 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
May influence DNA replication and cell cycle processes, potentially impacting MCMDC2 activity. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Affects various signaling pathways, potentially influencing MCMDC2 function in DNA replication. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Modulates numerous signaling pathways; could indirectly affect MCMDC2's role in cell division and replication. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
Influences gene expression, which might indirectly impact MCMDC2. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Impacts cellular metabolism and could indirectly affect MCMDC2's role in DNA replication. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Affects signaling pathways and could indirectly influence MCMDC2 function. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
A known mTOR inhibitor, could indirectly affect DNA replication processes involving MCMDC2. | ||||||
Palbociclib | 571190-30-2 | sc-507366 | 50 mg | $315.00 | ||
A CDK4/6 inhibitor, may indirectly influence MCMDC2 through cell cycle regulation. | ||||||
N-Acetyl-L-cysteine | 616-91-1 | sc-202232 sc-202232A sc-202232C sc-202232B | 5 g 25 g 1 kg 100 g | $33.00 $73.00 $265.00 $112.00 | 34 | |
Provides antioxidant support, which might indirectly influence the function or expression of MCMDC2. | ||||||
β-Nicotinamide mononucleotide | 1094-61-7 | sc-212376 sc-212376A sc-212376B sc-212376C sc-212376D | 25 mg 100 mg 1 g 2 g 5 g | $92.00 $269.00 $337.00 $510.00 $969.00 | 4 | |
Boosts NAD+ levels, potentially influencing cellular processes including those involving MCMDC2. | ||||||