C5 Activators
C5 Activators refer to a group of chemical entities that modulate the activity of the C5 protein component, an essential element of the complement system. The complement system is an intricate part of the immune response, functioning primarily in the defense against microbial pathogens. It consists of a series of proteins that work in a cascade manner, resulting in the opsonization of pathogens, chemotactic attraction of immune cells, and formation of the membrane attack complex leading to the lysis of targeted cells. The C5 protein, specifically, plays a pivotal role in the latter stages of this cascade, giving rise to C5a and C5b fragments upon its activation. C5a is a potent anaphylatoxin that attracts and activates various immune cells, while C5b initiates the assembly of the membrane attack complex.
C5 activators, as their name suggests, stimulate or enhance the activation of the C5 protein. By doing so, they can potentially increase the generation of C5-derived fragments, influencing the downstream effects associated with them. Given the crucial role of the complement system in innate immunity, it's clear that any modulation of its components can significantly affect immune responses. Understanding the molecular mechanisms of C5 activators can provide insights into the intricacies of the complement system and its broader implications in immunology. While the exact chemical structures and mechanisms of action of various C5 activators might differ, their overarching role is to augment the activity of the C5 protein in the complement cascade.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, found in the turmeric plant, has anti-inflammatory effects which might influence the regulation of various immune-related proteins, potentially including C5. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, found in grapes, has been known to modulate cellular pathways associated with inflammation and immunity, potentially influencing C5 expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid present in many fruits and vegetables, has demonstrated anti-inflammatory and immunomodulatory effects, which could affect C5 expression. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, abundant in green tea, has antioxidant properties. Its role in modulating inflammatory pathways could influence the expression of proteins like C5. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $153.00 $292.00 $489.00 $1325.00 $8465.00 $933.00 | 22 | |
Sulforaphane, found in cruciferous vegetables, has been shown to exert anti-inflammatory effects, possibly modulating C5 expression. | ||||||
Salicylic acid | 69-72-7 | sc-203374 sc-203374A sc-203374B | 100 g 500 g 1 kg | $47.00 $94.00 $119.00 | 3 | |
Salicylic Acid, a plant hormone, has been known for its role in inflammation regulation. This might impact the regulation of immune-related proteins like C5. | ||||||
Fisetin | 528-48-3 | sc-276440 sc-276440A sc-276440B sc-276440C sc-276440D | 50 mg 100 mg 500 mg 1 g 100 g | $52.00 $79.00 $104.00 $156.00 $2913.00 | 7 | |
Fisetin, a flavonoid found in strawberries, has anti-inflammatory and antioxidant properties which might modulate the expression of immune-related proteins like C5. | ||||||
Piperine | 94-62-2 | sc-205809 sc-205809A | 5 g 25 g | $37.00 $146.00 | 3 | |
Piperine, a major component of black pepper, has shown immunomodulatory effects, suggesting a potential role in regulating proteins such as C5. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Kaempferol, a flavonoid found in various plants, has anti-inflammatory properties which might influence the expression of immune proteins, potentially including C5. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine, found in several plants, has shown to have anti-inflammatory and immunomodulatory effects, which could affect C5 expression. | ||||||