CFAP298, also known as C21orf59 or 1110004E09Rik, is a protein encoded by the C21orf59 gene. This protein has been identified in several organisms, including humans. Although the precise biological function of CFAP298 is still under investigation, initial studies have suggested its involvement in ciliary function and motility. Cilia are hair-like projections on the surface of many eukaryotic cells, which play crucial roles in several physiological processes, including cell movement and signal transduction. Any aberrations in ciliary function can lead to a range of disorders, collectively referred to as ciliopathies.
Inhibitors targeting CFAP298 are chemicals or molecules designed to modulate or reduce the activity of this protein. These inhibitors can bind to CFAP298, thereby altering its function or stopping it from interacting with other proteins or molecules within the cell. By inhibiting CFAP298, researchers aim to understand its role in ciliary function better and elucidate any associated cellular pathways or processes. These inhibitors are valuable tools in basic biological research, offering insights into the molecular and cellular mechanisms by which CFAP298 operates. Furthermore, the study of CFAP298 inhibitors contributes to a broader understanding of cilia biology and the intricacies of cellular signaling and movement processes.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin is a broad-spectrum DNA intercalating agent that can affect multiple genes and may indirectly influence CFAP298 expression. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
This antibiotic binds DNA and interferes with RNA synthesis, potentially reducing CFAP298 mRNA synthesis. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-Fluorouracil is an antimetabolite that inhibits DNA synthesis, potentially affecting CFAP298 expression indirectly. | ||||||
Hydroxyurea | 127-07-1 | sc-29061 sc-29061A | 5 g 25 g | $76.00 $255.00 | 18 | |
Hydroxyurea inhibits ribonucleotide reductase, affecting DNA synthesis and potentially influencing CFAP298 expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
This compound specifically binds to GC-rich DNA regions, potentially altering CFAP298 gene transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An HDAC inhibitor, Trichostatin A can modify chromatin structure, potentially affecting CFAP298 gene transcription. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
It can alter gene expression via Nrf2-mediated oxidative stress response, potentially impacting CFAP298 indirectly. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor which may influence various cellular pathways, potentially affecting CFAP298 expression. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Rho-associated protein kinase (ROCK) inhibitor, which may indirectly influence CFAP298 gene expression. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
This is a TGF-beta receptor inhibitor, potentially influencing cellular pathways affecting CFAP298 expression. | ||||||