C1orf68 Activators
C1orf68 activators refer to a group of compounds that modulate the activity of the protein encoded by the C1orf68 gene, which is a locus on chromosome 1 that has been designated an 'open reading frame', indicating the region of the genome is believed to be translated into a protein. The exact biological function of C1orf68 is not thoroughly characterized, but it is understood that activators of this protein may play a role in its functional regulation.
Activation of C1orf68 by chemical activators can occur through direct or indirect mechanisms. Direct activators may bind to the protein and induce a conformational change that increases its biological activity. This may involve allosteric modulation where the activator binds to a site other than the active site. Such a binding event can alter the protein's structure in a way that enhances its interaction with other cellular components or substrates, thereby increasing its activity. Indirect activators might influence the expression levels of the C1orf68 protein, potentially by affecting the transcriptional machinery or by stabilizing the mRNA to increase protein translation. Other indirect methods of activation could include the modulation of signaling pathways that either control the synthesis of C1orf68 or alter its post-translational modifications, which in turn could affect the protein's stability, localization, or interaction with other cellular proteins.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Etoposide (VP-16) | 33419-42-0 | sc-3512B sc-3512 sc-3512A | 10 mg 100 mg 500 mg | $32.00 $170.00 $385.00 | 63 | |
Etoposide induces DNA damage and triggers a p53-mediated response, which can indirectly affect proteins associated with DNA damage response and repair. | ||||||
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $173.00 $418.00 | 43 | |
Doxorubicin causes DNA damage and initiates a p53-mediated response, potentially influencing proteins involved in DNA damage response. | ||||||
Fluorouracil | 51-21-8 | sc-29060 sc-29060A | 1 g 5 g | $36.00 $149.00 | 11 | |
5-Fluorouracil inhibits thymidylate synthase, causing DNA damage and initiating a p53-mediated response, which could influence proteins associated with DNA repair. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $169.00 $299.00 | 66 | |
Tunicamycin inhibits N-linked glycosylation and induces an unfolded protein response, potentially affecting proteins associated with these processes. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Rapamycin inhibits mTOR, affecting protein synthesis and autophagy, potentially influencing proteins involved in these processes. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $40.00 $82.00 $256.00 | 127 | |
Cycloheximide inhibits protein synthesis, which can impact proteins associated with this process. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A disrupts Golgi function and can influence proteins associated with protein trafficking. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $56.00 $260.00 $980.00 | 163 | |
MG132 inhibits the proteasome, affecting protein degradation, which could influence proteins involved in these pathways. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 inhibits PI3K, affecting AKT signaling, potentially influencing associated proteins. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Staurosporine inhibits protein kinases, affecting multiple signaling pathways and potentially influencing associated proteins. | ||||||