C1orf172_1810019J16Rik, while not exhaustively characterized in cellular signaling, can be postulated to interact with or be influenced by several predominant pathways within the cell. Chemical inhibitors such as PD98059 and U0126, which target MEK, play a vital role in disrupting the MAPK/ERK signaling. This disruption is key as numerous proteins function within or are influenced by this pathway. Similarly, compounds like LY294002 and Wortmannin serve as inhibitors to the PI3K/Akt pathway. This inhibition can substantially affect proteins that are either downstream or regulated by PI3K/Akt signaling.
Furthermore, the mTOR signaling pathway, impacted by the inhibitor Rapamycin, orchestrates various cellular processes, from protein synthesis to autophagy. The modulation of this pathway invariably affects a spectrum of proteins. Other inhibitors such as SB203580 and SP600125, which target p38 MAPK and JNK respectively, highlight the intricate interplay of cellular pathways. Y-27632's role as a ROCK inhibitor indicates how Rho/ROCK signaling can be manipulated, affecting proteins within its fold.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor that disrupts the MAPK/ERK signaling. If C1orf172_1810019J16Rik interacts or is regulated by this pathway, PD98059 can indirectly inhibit its function or expression. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor that dampens the PI3K/Akt pathway. If C1orf172_1810019J16Rik functions within or is influenced by this pathway, its activity can be altered by this inhibitor. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
mTOR inhibitor, impacting the mTOR signaling pathway. If C1orf172_1810019J16Rik is associated with mTOR signaling, Rapamycin can indirectly modulate its function. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor targeting the p38 MAPK pathway. If C1orf172_1810019J16Rik operates within this route, SB203580 can indirectly affect its role. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that alters the JNK signaling pathway. If C1orf172_1810019J16Rik participates in or is influenced by JNK signaling, this inhibitor can modify its function. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
PI3K inhibitor affecting the PI3K/Akt pathway. If C1orf172_1810019J16Rik interacts with or is regulated by this pathway, Wortmannin can alter its activity. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
ROCK inhibitor impacting the Rho/ROCK signaling. If C1orf172_1810019J16Rik is involved in this signaling, its function can be indirectly inhibited by Y-27632. | ||||||
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
NF-κB pathway inhibitor. If C1orf172_1810019J16Rik is part of or regulated by the NF-κB signaling pathway, its function can be indirectly impacted by BAY 11-7082. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
PKC inhibitor targeting various isoforms of protein kinase C. If C1orf172_1810019J16Rik interacts with or is regulated by PKC, Go6983 can modify its function. | ||||||
IWP-2 | 686770-61-6 | sc-252928 sc-252928A | 5 mg 25 mg | $94.00 $286.00 | 27 | |
Wnt processing inhibitor. Though the Wnt pathway is excluded from direct considerations, if C1orf172_1810019J16Rik has indirect interactions with Wnt signaling, IWP-2 can affect it. | ||||||