C1orf123_0610037L13Rik Activators
C1orf123_0610037L13Rik Activators encompass a range of chemical compounds that indirectly foster the functional activity of C1orf123_0610037L13Rik via discrete signaling pathways. Forskolin and Dibutyryl-cAMP, by elevating intracellular cAMP, activate PKA which may phosphorylate proteins that modulate the function of C1orf123_0610037L13Rik. Meanwhile, Epigallocatechin gallate and Genistein, as kinase inhibitors, reduce competitive phosphorylation thus favoring pathways where C1orf123_0610037L13Rik has a positive role. PMA, as a PKC activator, and ionomycin, by increasing intracellular calcium, potentially facilitate the engagement of C1orf123_0610037L13Rik in signaling cascades by altering the phosphorylation state of associated regulatory proteins. D-erythro-Sphingosine-1-phosphate stands out for its ability to activate specific receptors that may enhance C1orf123_0610037L13Rik's activity through lipid signaling pathways.
In addition, the PI3K inhibitor LY 294002, MEK inhibitor U0126, and p38 MAPK inhibitor SB 203580 might shift cellular signaling dynamics towards pathways that C1orf123_0610037L13Rik positively influences, thereby amplifying its functional activity. Staurosporine, although a broad-spectrum kinase inhibitor, could selectively enhance C1orf123_0610037L13Rik's role by preferentially inhibiting kinases that negatively regulate its associated pathways. Lastly, calcium modulators like A23187 could stimulate calcium-dependent signaling pathways, leading to the activation of proteins and processes that synergistically enhance the activity of C1orf123_0610037L13Rik. Collectively, these activators, through their targeted biochemical actions, have the potential to bolster the functional activity of C1orf123_0610037L13Rik without necessitating an upregulation of its expression or direct activation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
This polyphenol inhibits a variety of kinases, which may reduce inhibitory phosphorylation events. This reduction in inhibitory signals could enhance signaling pathways where C1orf123_0610037L13Rik is a positive effector. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA activates protein kinase C (PKC), which might lead to the phosphorylation of proteins that work synergistically with C1orf123_0610037L13Rik, thereby enhancing its functional activity. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
As a calcium ionophore, ionomycin increases intracellular calcium levels, which may activate calcium-dependent protein kinases that could, in turn, enhance signaling pathways involving C1orf123_0610037L13Rik. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
This lipid signaling molecule activates D-erythro-Sphingosine-1-phosphate receptors, potentially modulating intracellular signaling cascades that could amplify the functional activity of C1orf123_0610037L13Rik. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
As a PI3K inhibitor, LY 294002 could reduce competitive signaling pathways, thus possibly enhancing pathways where C1orf123_0610037L13Rik is a part of the positive regulation of cellular processes. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
By inhibiting p38 MAPK, SB 203580 could potentiate alternative signaling routes that may include C1orf123_0610037L13Rik as a positive effector, thus enhancing its role in such pathways. | ||||||
Dibutyryl-cAMP | 16980-89-5 | sc-201567 sc-201567A sc-201567B sc-201567C | 20 mg 100 mg 500 mg 10 g | $45.00 $130.00 $480.00 $4450.00 | 74 | |
This cAMP analog can mimic the effect of endogenous cAMP and activate PKA, potentially enhancing the functional activity of C1orf123_0610037L13Rik through PKA-dependent signaling mechanisms. | ||||||
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $150.00 $388.00 | 113 | |
Despite being a broad-spectrum kinase inhibitor, Staurosporine may preferentially inhibit kinases that negatively regulate the pathways in which C1orf123_0610037L13Rik is a positive participant, thereby indirectly enhancing its activity. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
As a tyrosine kinase inhibitor, Genistein could prevent phosphorylation that otherwise suppresses pathways involving C1orf123_0610037L13Rik, potentially allowing better functional expression of C1orf123_0610037L13Rik's activities. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
This ionophore increases intracellular calcium levels, which might activate downstream calcium-dependent proteins and pathways, possibly leading to enhanced functional activities of C1orf123_0610037L13Rik. | ||||||