C17orf75 Inhibitors
C17orf75 can contain PI3K inhibitors like Wortmannin and LY294002 prevent the phosphorylation and activation of downstream proteins in the AKT pathway. Similarly, mTOR inhibitors like Rapamycin can suppress cell growth and proliferation, which could indirectly affect proteins that interact with or are regulated by the mTOR pathway. Inhibitors targeting the MAPK/ERK pathway, such as PD98059 and U0126, are designed to block the phosphorylation of MEK, thereby inhibiting the activation of ERK and affecting downstream protein function. Inhibitors like SB203580, SP600125, and Y-27632 target other kinases involved in stress responses, apoptosis, and cytoskeletal organization, potentially altering the function of proteins associated with these processes.
Small molecules like Gefitinib and Dasatinib inhibit specific tyrosine kinases, which can influence various cellular processes, including cell division, apoptosis, and differentiation. HDAC inhibitors like Trichostatin A can alter gene expression profiles, impacting protein synthesis and function. Proteasome inhibitors such as Bortezomib disrupt the degradation of cellular proteins, leading to effects on cell cycle and stress response proteins.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Inhibits PI3K, which is part of the AKT signaling pathway that regulates various cellular processes, including metabolism, growth, and survival. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A specific inhibitor of PI3K, which could downregulate AKT pathway activity potentially affecting proteins regulated by this pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Binds to FKBP12 and inhibits mTOR, a key regulator of cell growth and proliferation, possibly affecting proteins controlled by mTOR signaling. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibits MEK, which is involved in the MAPK/ERK pathway, potentially affecting the function of proteins that are downstream of this signaling cascade. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
A p38 MAPK inhibitor, which could modulate inflammatory responses and other cellular processes, potentially influencing associated proteins. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
Inhibits JNK, potentially altering apoptosis and other cellular processes that could affect proteins regulated by JNK signaling. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Inhibits ROCK, which could affect cell shape, motility, and possibly proteins involved in these processes. | ||||||
Gefitinib | 184475-35-2 | sc-202166 sc-202166A sc-202166B sc-202166C | 100 mg 250 mg 1 g 5 g | $62.00 $112.00 $214.00 $342.00 | 74 | |
Inhibits EGFR tyrosine kinase, potentially affecting downstream signaling pathways and associated proteins. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
A SRC-family tyrosine kinase inhibitor, potentially affecting multiple cellular processes and possibly the function of related proteins. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Inhibits histone deacetylases (HDACs), potentially affecting gene expression and proteins regulated by chromatin structure. | ||||||