Date published: 2025-9-21

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C17orf75 Antibody (H-17): sc-81862

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Datasheets
  • C17orf75 Antibody (H-17) is a mouse monoclonal IgG1 κ C17orf75 antibody, cited in 1 publications, provided at 100 µg/ml
  • raised against recombinant C17orf75 of human origin
  • recommended for detection of C17orf75 of human origin by WB, IP, IF and ELISA
  • At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for C17orf75 Antibody (H-17). This work is in progress.

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C17orf75 Antibody (H-17) is a mouse monoclonal IgG1 kappa light chain antibody that detects C17orf75 protein of human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-C17orf75 antibody (H-17) is available as a non-conjugated monoclonal isotype antibody. C17orf75 protein, also known as chromosome 17 open reading frame 75, consists of 396 amino acids and is encoded by a gene located on human chromosome 17, which harbors critical tumor suppressor genes such as p53 and BRCA1. p53 protein plays a vital role in maintaining cellular genetic integrity by regulating cell fate decisions, including DNA repair and apoptosis, while BRCA1 is essential for DNA repair mechanisms and is a key factor in hereditary breast and ovarian cancers. C17orf75′s presence in this genomic context suggests important regulatory functions, potentially influencing pathways related to tumor suppression and cellular stress responses. Understanding C17orf75′s interactions and functions can provide insights into its role in cancer biology and other diseases associated with chromosome 17, making C17orf75 (H-17) antibody a valuable tool for researchers studying these critical pathways.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

C17orf75 Antibody (H-17) References:

  1. Birt-Hogg-Dubé Syndrome.  |  Welsch, MJ., et al. 2005. Int J Dermatol. 44: 668-73. PMID: 16101870
  2. BLIMP1 regulates cell growth through repression of p53 transcription.  |  Yan, J., et al. 2007. Proc Natl Acad Sci U S A. 104: 1841-6. PMID: 17264218
  3. Neurofibromatosis 1, and Not TP53, seems to be the main target of chromosome 17 deletions in de novo acute myeloid leukemia.  |  Suela, J., et al. 2007. J Clin Oncol. 25: 1151-2; author reply 1152-3. PMID: 17369586
  4. Quantification of N-acetylaspartic acid in urine by LC-MS/MS for the diagnosis of Canavan disease.  |  Al-Dirbashi, OY., et al. 2007. J Inherit Metab Dis. 30: 612. PMID: 17632691
  5. Genetic causes of brain tumors: neurofibromatosis, tuberous sclerosis, von Hippel-Lindau, and other syndromes.  |  Farrell, CJ. and Plotkin, SR. 2007. Neurol Clin. 25: 925-46, viii. PMID: 17964021
  6. Breast cancer risk among male BRCA1 and BRCA2 mutation carriers.  |  Tai, YC., et al. 2007. J Natl Cancer Inst. 99: 1811-4. PMID: 18042939
  7. Novel deletion mutation in GFAP gene in an infantile form of Alexander disease.  |  Murakami, N., et al. 2008. Pediatr Neurol. 38: 50-2. PMID: 18054694
  8. Strategies for ovarian cancer prevention.  |  Dann, RB., et al. 2007. Obstet Gynecol Clin North Am. 34: 667-86, viii. PMID: 18061863
  9. Susceptibility to breast cancer: hereditary syndromes and low penetrance genes.  |  Nusbaum, R., et al. Breast Dis. 27: 21-50. PMID: 17917139

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

C17orf75 Antibody (H-17)

sc-81862
100 µg/ml
$316.00

I am using C17orf75 (H-17): sc-81862 for immunofluorescence, what dilution of this antibody should I use?

Asked by: jenniferc
Thank you for your question. We recommend a starting dilution of 1:50. However, optimal antibody concentration should be determined by titration. Please find our full immunofluorescence protocol here: https://www.scbt.com/scbt/resources/protocols/immunofluorescence-cell-staining
Answered by: Technical Support
Date published: 2017-03-24
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Rated 5 out of 5 by from Great specificity for C17orf75 in Western BlotThis antibody detects over-expressed human C17orf75 in transfected lysate sc-116623. -SCBT QC
Date published: 2023-09-14
Rated 5 out of 5 by from Produced beautiful immunofluorescence nuclearProduced beautiful immunofluorescence nuclear staining in paraformaldehyde-fixed HeLa cells. -SCBT QC
Date published: 2015-04-30
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C17orf75 Antibody (H-17) is rated 5.0 out of 5 by 3.
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