C16orf65 Activators
C16orf65 Activators are a set of chemical compounds that, through their influence on various signaling pathways and cellular processes, have the potential to enhance the functional activity of C16orf65. Forskolin, by increasing cAMP levels, activates PKA, which could phosphorylate proteins including C16orf65 or its associated substrates, thereby enhancing its activity. Ionomycin and A23187, both acting as calcium ionophores, raise intracellular calcium levels and could activate calcium-dependent kinases that may interact with C16orf65, enhancing its functional role. Phorbol 12-myristate 13-acetI apologize for the incomplete response. Let me continue with the narrative description for C16orf65 Activators based on the table provided.
C16orf65 Activators encompass a variety of chemical compounds that are involved in diverse biochemical signaling pathways, with the potential to augment the functional activity of C16orf65 indirectly. Forskolin elevates intracellular cAMP, which activates protein kinase A (PKA). PKA, in turn, could phosphorylate proteins that are part of the pathways involving C16orf65, thus enhancing its activity. Similarly, ionomycin and A23187, both calcium ionophores, increase intracellular calcium levels, which may activate calcium-dependent kinases that interact with C16orf65, potentially leading to its enhanced activity. Phorbol 12-myristate 13-acetate (PMA), by activating protein kinase C (PKC), could phosphorylate substrates that influence pathways in which C16orf65 is involved, leading to enhanced activity of C16orf65. Furthermore, epigallocatechin gallate (EGCG), via its inhibition of competitive kinase pathways, could shift the cellular signaling balance in favor of pathways that increase C16orf65 activity. Sphingosine-1-phosphate (S1P) and its receptor-mediated signaling, along with the PI3K inhibitor LY294002, may affect downstream proteins and signaling cascades that intersect with the functional roles of C16orf65.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $76.00 $265.00 | 80 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels. Calcium signaling is vital for many cellular processes, potentially enhancing C16orf65 activity by activating calcium-dependent kinases that interact with C16orf65. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
PMA is a diester of phorbol and acts as a potent activator of protein kinase C (PKC). PKC activation could lead to the phosphorylation of proteins involved in pathways that could indirectly enhance the activity of C16orf65. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $42.00 $72.00 $124.00 $238.00 $520.00 $1234.00 | 11 | |
EGCG is a polyphenol found in green tea that inhibits several protein kinases. By inhibiting competitive pathways, EGCG could shift the cellular signaling balance, thereby enhancing pathways that upregulate the activity of C16orf65. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $162.00 $316.00 $559.00 $889.00 $1693.00 | 7 | |
S1P is a bioactive lipid that acts through G protein-coupled receptors to influence several signaling pathways, including those related to cell survival and proliferation that could indirectly enhance the activity of C16orf65. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a selective inhibitor of phosphoinositide 3-kinases (PI3K), which can alter multiple signaling pathways. Inhibition of PI3K could indirectly enhance C16orf65 activity by affecting downstream signaling proteins. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is an inhibitor of mitogen-activated protein kinase kinase (MEK), which could lead to the alteration of MAPK pathway signaling. This alteration could indirectly increase the activity of C16orf65 through changes in the cellular signaling milieu. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAPK. By inhibiting p38 MAPK, it may indirectly enhance C16orf65 activity by altering the balance of signaling pathways that intersect with those involving C16orf65. | ||||||
Zoledronic acid, anhydrous | 118072-93-8 | sc-364663 sc-364663A | 25 mg 100 mg | $90.00 $251.00 | 5 | |
Zoledronic acid is a bisphosphonate that inhibits farnesyl pyrophosphate synthase, potentially affecting protein prenylation. This could indirectly enhance C16orf65 activity by altering the localization or function of proteins that interact with C16orf65. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $94.00 $349.00 | 114 | |
Thapsigargin is a sesquiterpene lactone that inhibits the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), leading to increased intracellular calcium. This could enhance C16orf65 activity by modulating calcium-dependent signaling pathways. | ||||||
A23187 | 52665-69-7 | sc-3591 sc-3591B sc-3591A sc-3591C | 1 mg 5 mg 10 mg 25 mg | $54.00 $128.00 $199.00 $311.00 | 23 | |
A23187 is an ionophore that selectively increases intracellular calcium concentration, potentially enhancing C16orf65 activity by activating calcium-dependent processes that could influence C16orf65's functional role. | ||||||