c-Myc Inhibitors
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
10058-F4 | 403811-55-2 | sc-213577 sc-213577B sc-213577A sc-213577C | 5 mg 10 mg 25 mg 50 mg | $81.00 $134.00 $241.00 $426.00 | 9 | |
10058-F4 is a selective inhibitor of c-Myc, disrupting its interaction with essential transcriptional co-factors. By binding to the Myc-Max heterodimer, it impedes DNA binding and transcriptional activation, leading to altered gene expression profiles. This compound influences cellular proliferation and apoptosis pathways, showcasing its ability to modulate oncogenic signaling networks. Its unique mechanism highlights the intricate balance of transcriptional regulation in cellular homeostasis. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $231.00 $863.00 | 1 | |
JQ1 is a potent inhibitor of the bromodomain and extraterminal (BET) family of proteins, including c-Myc. It displaces BET proteins from chromatin, leading to the downregulation of c-Myc expression. | ||||||
10074-G5 | 413611-93-5 | sc-213578 sc-213578B sc-213578A sc-213578C sc-213578D | 5 mg 10 mg 25 mg 100 mg 1 g | $82.00 $154.00 $330.00 $982.00 $2045.00 | 3 | |
10074-G5 (CAS 413611-93-5) is a small molecule known for inhibiting the c-Myc protein by disrupting its interaction with Max, a key partner in c-Myc′s transcriptional activity. By preventing the formation of the c-Myc/Max heterodimer, 10074-G5 interferes with c-Myc′s ability to regulate gene expression. This inhibition is of interest in scientific research studying c-Myc′s role in cell growth, gene regulation, and molecular pathways. | ||||||
CX-5461 | 1138549-36-6 | sc-507275 | 5 mg | $245.00 | ||
CX-5461 is a selective inhibitor of RNA polymerase I transcription, which leads to the downregulation of c-Myc expression as c-Myc relies on RNA polymerase I for its transcription. | ||||||
KJ Pyr 9 | 581073-80-5 | sc-507276 | 5 mg | $140.00 | ||
KJ-Pyr-9 is a small molecule inhibitor that disrupts the interaction between c-Myc and its cofactor TRRAP, leading to the inhibition of c-Myc transcriptional activity. | ||||||
Myci975 | 2289691-01-4 | sc-507277 sc-507277A sc-507277B | 100 mg 250 mg 1 g | $420.00 $950.00 $3219.00 | ||
MYCi975 is a small molecule inhibitor that selectively disrupts the interaction between c-Myc and its partner Max, inhibiting c-Myc-driven transcriptional activity. | ||||||
10074-A4 | 312631-87-1 | sc-507286 | 10 mg | $429.00 | ||
Similar to 10074-G5, this compound disrupts the formation of the c-Myc-Max complex, inhibiting c-Myc-mediated transcription. | ||||||
BETd-246 | 2140289-17-2 | sc-507288 | 5 mg | $1071.00 | ||
BETd-246 is a potent inhibitor of BET proteins, including c-Myc. It competes with the bromodomain binding pocket, disrupting the interaction between c-Myc and BET proteins. | ||||||
PI3K/HDAC Inhibitor | 1339928-25-4 | sc-364584 sc-364584A | 5 mg 10 mg | $347.00 $471.00 | ||
PI3K/HDAC Inhibitor is a dual inhibitor that targets both histone deacetylases (HDACs) and phosphatidylinositol 3-kinase (PI3K). It indirectly affects c-Myc by modulating its upstream signaling pathways. | ||||||