MF: C23H24N8O4S MW: 508.55 An inhibitor of HDAC1, HDAC3, HDAC6, HDAC8, HDAC10, and HDAC11.
Protein-Interacting Inhibitors, Activators & Substrates
PI 3-kinase Inhibitors
PI3K/HDAC Inhibitor (CAS 1339928-25-4)
PI3K/HDAC Inhibitor is an inhibitor of HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, HDAC10, and HDAC11
C 23H 24N 8O 4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use. *
Certificate of Analysis for lot specific data (including water content).
PI3K/HDAC Inhibitor is a dual PI 3-kinase and HDAC inhibitor for PI3Kα, HDAC1 (IC
50 = 19 nM), HDAC3 (IC 50 = 1.7 nM), HDAC6 (IC 50 = 27 nM), HDAC8 (IC 50 = 191 nM), HDAC10 (IC 50 = 2.8 nM), and HDAC11 (IC 50 = 5.4 nM).
Soluble in DMSO (102 mg/ml at 25 °C), water (<1 mg/ml at 25 °C), and ethanol (<1 mg/ml at 25 °C).
Store at -20° C
50 = 1.7 nM; HDAC3: IC 50 = 1.8 nM; HDAC10: IC 50 = 2.8 nM; HDAC2: IC 50 = 5.0 nM; PI3Kα: IC 50 = 19 nM
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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