Molecular structure of Myci975, CAS Number: 2289691-01-4
Myci975 (CAS 2289691-01-4)
Alternate Names:
4′-Chloro-6-((4-chlorobenzyl)oxy)-3-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-5-yl)-3′-(trifluoromethyl)-[1,1′-biphenyl]-2-ol
CAS Number:
2289691-01-4
Molecular Weight:
561.3
Molecular Formula:
C25H16Cl2F6N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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Myci975 (CAS 2289691-01-4) References
- Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy. | Han, H., et al. 2019. Cancer Cell. 36: 483-497.e15. PMID: 31679823
- Turning Up the Heat on MYC: Progress in Small-Molecule Inhibitors. | Truica, MI., et al. 2021. Cancer Res. 81: 248-253. PMID: 33087323
- Super-enhancer-associated TMEM44-AS1 aggravated glioma progression by forming a positive feedback loop with Myc. | Bian, E., et al. 2021. J Exp Clin Cancer Res. 40: 337. PMID: 34696771
- A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression. | Holmes, AG., et al. 2022. Sci Adv. 8: eabh3635. PMID: 35476451
- MYC as a therapeutic target for the treatment of triple-negative breast cancer: preclinical investigations with the novel MYC inhibitor, MYCi975. | Tang, M., et al. 2022. Breast Cancer Res Treat. 195: 105-115. PMID: 35908121
- Therapeutic Targeting of MYC in Head and Neck Squamous Cell Carcinoma. | Liu, S., et al. 2022. Oncoimmunology. 11: 2130583. PMID: 36211811
- Degradation of MYC by the mutant p53 reactivator drug, COTI-2 in breast cancer cells. | Tang, M., et al. 2023. Invest New Drugs. 41: 541-550. PMID: 37233863
- Pharmacological inhibition of MYC to mitigate chemoresistance in preclinical models of squamous cell carcinoma. | Liu, S., et al. 2024. Theranostics. 14: 622-639. PMID: 38169606
- MYC Inhibition Potentiates CD8+ T Cells Against Multiple Myeloma and Overcomes Immunomodulatory Drug Resistance. | Davis, LN., et al. 2024. Clin Cancer Res.. PMID: 38723281
Inhibitor of:
c-Myc, ISY1, Myc1, MYCBP, and S-Myc.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Myci975, 100 mg | sc-507277 | 100 mg | $420.00 | |||
Myci975, 250 mg | sc-507277A | 250 mg | $950.00 | |||
Myci975, 1 g | sc-507277B | 1 g | $3219.00 |