Molecular structure of KJ Pyr 9, CAS Number: 581073-80-5
KJ Pyr 9 (CAS 581073-80-5)
Alternate Names:
4-[2-(2-furanyl)-6-(4-nitrophenyl)-4-pyridinyl]-benzamide
CAS Number:
581073-80-5
Molecular Weight:
385.4
Molecular Formula:
C22H15N3O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
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KJ Pyr 9 (CAS 581073-80-5) References
- Inhibitor of MYC identified in a Kröhnke pyridine library. | Hart, JR., et al. 2014. Proc Natl Acad Sci U S A. 111: 12556-61. PMID: 25114221
- Targeting MYC sensitizes malignant mesothelioma cells to PAK blockage-induced cytotoxicity. | Tan, Y., et al. 2017. Am J Cancer Res. 7: 1724-1737. PMID: 28861328
- A selective high affinity MYC-binding compound inhibits MYC:MAX interaction and MYC-dependent tumor cell proliferation. | Castell, A., et al. 2018. Sci Rep. 8: 10064. PMID: 29968736
- Pre-treatment with the CDK4/6 inhibitor palbociclib improves the efficacy of paclitaxel in TNBC cells. | Cretella, D., et al. 2019. Sci Rep. 9: 13014. PMID: 31506466
- Isolation and Characterization of Two Novel Colorectal Cancer Cell Lines, Containing a Subpopulation with Potential Stem-Like Properties: Treatment Options by MYC/NMYC Inhibition. | Schulte Am Esch, JSA., et al. 2020. Cancers (Basel). 12: PMID: 32927768
- Novel Primary Human Cancer Stem-Like Cell Populations from Non-Small Cell Lung Cancer: Inhibition of Cell Survival by Targeting NF-κB and MYC Signaling. | Windmöller, BA., et al. 2021. Cells. 10: PMID: 33925297
- Suppression of PI3K/Akt/mTOR/c-Myc/mtp53 Positive Feedback Loop Induces Cell Cycle Arrest by Dual PI3K/mTOR Inhibitor PQR309 in Endometrial Cancer Cell Lines. | Hsin, IL., et al. 2021. Cells. 10: PMID: 34831139
- The Diminishment of Novel Endometrial Carcinoma-Derived Stem-like Cells by Targeting Mitochondrial Bioenergetics and MYC. | Helweg, LP., et al. 2022. Int J Mol Sci. 23: PMID: 35269569
- Targeting Key Signaling Pathways in Glioblastoma Stem Cells for the Development of Efficient Chemo- and Immunotherapy. | Helweg, LP., et al. 2022. Int J Mol Sci. 23: PMID: 36361720
- Targeting TNF/IL-17/MAPK pathway in hE2A-PBX1 leukemia: effects of OUL35, KJ-Pyr-9, and CID44216842. | Luo, H., et al. 2024. Haematologica. 109: 2092-2110. PMID: 38385270
Inhibitor of:
B-Myc, c-Myc, ISY1, Myc, Myc1, MYCBP, N-Myc, and S-Myc.Activator of:
Mxi1.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
KJ Pyr 9, 5 mg | sc-507276 | 5 mg | $140.00 |