BC053393, a protein of growing interest in cellular biology, plays a critical role in the modulation of transcriptional regulation and cellular processes related to cell growth and differentiation. While the specific functions of BC053393 are still under exploration, its intricate connections with various signaling pathways underscore its significance in cellular physiology. Understanding the complex network of interactions involving BC053393 is crucial for deciphering its functional roles in cellular contexts. BC053393 inhibition is potentially achieved through a range of compounds targeting key signaling pathways and cellular processes associated with BC053393 function. These inhibitors may impact BC053393 expression and activity indirectly by modulating pathways such as p38 MAPK, MAPK/ERK, PI3K/Akt, JNK, TGF-β, Wnt/β-catenin, Rho/ROCK, and mTOR. For instance, SB-203580 blocks p38 MAPK activity, potentially influencing BC053393-mediated cellular processes related to transcriptional regulation and cell growth. Similarly, U0126 and PD0325901 target the MAPK/ERK pathway, potentially affecting BC053393 expression and function in the context of cellular growth and differentiation.
Among the inhibitors listed, GSK-3 Inhibitor IX and LY2090314 may specifically target the Wnt/β-catenin pathway, potentially influencing BC053393 indirectly through GSK-3 inhibition. These compounds shed light on the interconnectedness of BC053393 with Wnt signaling and its potential impact on cellular processes related to cell growth and differentiation. Additionally, the BET bromodomain inhibitor JQ1 and the mTOR inhibitor AZD8055 provide insights into the role of chromatin accessibility and the mTOR pathway in BC053393-mediated transcriptional regulation. In conclusion, BC053393 inhibitors serve as valuable tools for unraveling the functional significance of this protein in cellular processes. The potential diverse mechanisms of inhibition, targeting multiple signaling pathways, offer a nuanced perspective on the interconnected regulatory networks that converge on BC053393. Continued research into the precise functions of BC053393 and the effects of these inhibitors will undoubtedly contribute to a deeper understanding of the intricate molecular pathways governing cellular growth and differentiation.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
p38 MAPK inhibitor. SB-203580 affects the p38 MAPK pathway, potentially modulating BC053393 expression and function. By blocking p38 MAPK activity, this inhibitor indirectly influences BC053393-mediated cellular processes related to transcriptional regulation and cell growth. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor targeting the PI3K/Akt pathway. LY294002 disrupts the PI3K/Akt pathway, which crosstalks with BC053393 signaling. This interference may influence BC053393 expression and function, altering downstream cellular processes associated with transcriptional regulation and cellular differentiation. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
TGF-β receptor inhibitor. SB-431542 prevents the activation of TGF-β signaling, potentially influencing BC053393 by disrupting the TGF-β pathway. This interference may alter downstream cellular responses governed by BC053393, impacting transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Irreversible PI3K inhibitor. Inhibiting PI3K disrupts the PI3K/Akt pathway, which crosstalks with BC053393 signaling. This disruption may influence BC053393 expression and function, altering downstream cellular processes associated with transcriptional regulation and cellular differentiation. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor. SP600125 affects the JNK pathway, potentially modulating BC053393 expression and function in specific cellular contexts. By blocking JNK activity, this inhibitor indirectly influences BC053393-mediated cellular processes related to transcriptional regulation and cell growth. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $57.00 $184.00 $867.00 | 10 | |
GSK-3 inhibitor affecting the Wnt/β-catenin pathway. By inhibiting GSK-3, this compound may influence BC053393 indirectly, as GSK-3 participates in the regulation of the Wnt/β-catenin pathway, which crosstalks with BC053393 signaling. The modulation of this pathway may alter BC053393 expression and function, impacting transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
ROCK inhibitor. Y-27632 affects the Rho/ROCK pathway, potentially modulating BC053393 expression and function in specific cellular contexts. By inhibiting ROCK activity, this compound indirectly influences BC053393-mediated cellular processes related to transcriptional regulation and cell growth. | ||||||
LY2090314 | 603288-22-8 | sc-507359 | 5 mg | $175.00 | ||
GSK-3 inhibitor targeting the Wnt/β-catenin pathway. LY2090314 may influence BC053393 indirectly by inhibiting GSK-3, a key regulator of the Wnt/β-catenin pathway that intersects with BC053393 signaling. This interference may alter BC053393 expression and function, impacting transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||
(±)-JQ1 | 1268524-69-1 | sc-472932 sc-472932A | 5 mg 25 mg | $226.00 $846.00 | 1 | |
BET bromodomain inhibitor. (+/-)-JQ1 may influence BC053393 expression by targeting BET proteins, including BRD4. This inhibitor may affect chromatin accessibility and gene expression, indirectly modulating BC053393-mediated transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $160.00 $345.00 | 12 | |
mTOR inhibitor. AZD8055 disrupts the mTOR pathway, which crosstalks with BC053393 signaling. This interference may influence BC053393 expression and function, impacting transcriptional regulation and cellular processes related to cell growth and differentiation. | ||||||