Bax Activators
Items 1 to 10 of 11 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Stat3 Inhibitor III, WP1066 | 857064-38-1 | sc-203282 | 10 mg | $132.00 | 72 | |
Stat3 Inhibitor III, also known as WP1066, is notable for its ability to disrupt the Stat3 signaling pathway, which is crucial in various cellular processes. This compound selectively binds to the SH2 domain of Stat3, preventing its phosphorylation and subsequent dimerization. The inhibition alters downstream gene expression, impacting cellular proliferation and survival. Its unique interaction profile and kinetic behavior highlight its role in modulating transcriptional activity within the cell. | ||||||
ABT 263 | 923564-51-6 | sc-207241 | 5 mg | $240.00 | 16 | |
ABT-263 is a Bcl-2 family inhibitor that indirectly activates Bax by binding to and inhibiting anti-apoptotic proteins like Bcl-2 and Bcl-xL. This frees up pro-apoptotic proteins like Bim, allowing them to activate Bax. | ||||||
ABT 737 | 852808-04-9 | sc-207242 | 2.5 mg | $200.00 | 54 | |
Similar to ABT-263, ABT-737 is an inhibitor of Bcl-2 and Bcl-xL, promoting apoptosis by releasing pro-apoptotic proteins such as Bim and Bad to activate Bax. | ||||||
TW-37 | 877877-35-5 | sc-361387 sc-361387A | 10 mg 50 mg | $200.00 $860.00 | 2 | |
TW-37 is a small molecule inhibitor that disrupts Bcl-2 and Bcl-xL interactions with pro-apoptotic proteins, leading to Bax activation. | ||||||
HA14-1 | 65673-63-4 | sc-205911 sc-205911A | 5 mg 25 mg | $58.00 $205.00 | ||
HA14-1 is known to target anti-apoptotic proteins like Bcl-2, releasing Bax and allowing it to initiate apoptosis. | ||||||
Gossypol | 303-45-7 | sc-200501 sc-200501A | 25 mg 100 mg | $114.00 $225.00 | 12 | |
Gossypol functions as a Bcl-2 family inhibitor, promoting apoptosis by disrupting the interactions between anti-apoptotic proteins and Bax. | ||||||
Obatoclax | 803712-67-6 | sc-507476 | 10 mg | $348.00 | ||
GX15-070 inhibits various Bcl-2 family members, including Bcl-2, Bcl-xL, and Mcl-1, thus indirectly activating Bax. | ||||||
Sabutoclax | 1228108-65-3 | sc-472977 | 1 mg | $330.00 | ||
Sabutoclax inhibits multiple anti-apoptotic Bcl-2 family members, leading to the activation of Bax and apoptosis. | ||||||
A-1331852 | 1430844-80-6 | sc-507472 | 5 mg | $230.00 | ||
A-1331852 is a selective Bcl-xL inhibitor, disrupting the protective interaction between Bcl-xL and Bax, allowing Bax to promote apoptosis. | ||||||
WEHI-539 | 1431866-33-9 | sc-507317 | 5 mg | $233.00 | ||
WEHI-539 is a potent Bcl-xL inhibitor, enabling Bax activation and apoptosis induction. | ||||||