Gossypol is a male antifertility agent with antispermatogenic activity and has been shown to contain antitumor, anitviral, and antioxidant properties. Gossypol is a reversible inhibitor of PP2B (protein phosphatase 2B), mitotic kinesin Eg5, and PKC (protein kinase C). Gossypol also potentially inhibits PAF-R, Bcl-2, 5-LO (5-lipoxygenase), 12-LO, and leukotriene-induced guinea pig parenchyma contractions. Gossypol is an inhibitor of Bcl-xl, PKD and p107.
How long are stock solutions stable for? At what temperature?
Asked by: chemicalsmg
Thank you for your question. Stock solutions for sc-200501 are stable for up to 1 month if stored at -20ºC. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
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Jiang et alJiang et al. (PubMed ID 15015584) found that gossypol prevented the proliferation of human prostate cancer cells by blocking induction of TGFbeta1 and influencing the expression of cell cycle proteins. -SCBT Publication Review
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