Date published: 2025-10-15

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BAFL Activators

Activators targeting BANF family member 2, in the context of chemical compounds, are primarily approached through indirect pathways, especially those influencing chromatin remodeling and epigenetic regulation. Given the involvement of BANF proteins in nuclear architecture and chromatin structure, histone deacetylase (HDAC) inhibitors represent a significant category of these indirect activators. Compounds like Trichostatin A, Vorinostat, Valproic Acid, Sodium Butyrate, MS-275 (Entinostat), SAHA (Vorinostat), Romidepsin, Panobinostat, and Belinostat function by inhibiting histone deacetylases, leading to changes in chromatin structure, which could in turn influence the activity of BANF family proteins. These changes in chromatin accessibility and structure can have wide-ranging effects on gene expression and nuclear processes, potentially impacting proteins involved in maintaining nuclear architecture.

Additionally, DNA methyltransferase inhibitors like 5-Azacytidine and Decitabine represent another class of indirect activators. By altering DNA methylation patterns, these compounds can induce changes in gene expression and chromatin organization, which may affect the function of BANF proteins. Sirtinol, targeting sirtuin histone deacetylases, also falls into this category, potentially impacting chromatin dynamics and nuclear architecture relevant to BANF family proteins.

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Items 1 to 10 of 11 total

Display:

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$149.00
$470.00
$620.00
$1199.00
$2090.00
33
(3)

Trichostatin A, a histone deacetylase inhibitor, may indirectly affect chromatin remodeling processes associated with BANF proteins.

Suberoylanilide Hydroxamic Acid

149647-78-9sc-220139
sc-220139A
100 mg
500 mg
$130.00
$270.00
37
(2)

Vorinostat, another histone deacetylase inhibitor, could potentially influence nuclear architecture related to BANF proteins.

Valproic Acid

99-66-1sc-213144
10 g
$85.00
9
(1)

Valproic Acid, also a histone deacetylase inhibitor, may have an indirect impact on BANF family proteins through chromatin modification.

Sodium Butyrate

156-54-7sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$30.00
$46.00
$82.00
$218.00
19
(3)

Sodium Butyrate, a short-chain fatty acid and histone deacetylase inhibitor, might affect BANF proteins by altering chromatin structure.

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

5-Azacytidine, a DNA methyltransferase inhibitor, could indirectly influence BANF proteins via epigenetic modifications.

5-Aza-2′-Deoxycytidine

2353-33-5sc-202424
sc-202424A
sc-202424B
25 mg
100 mg
250 mg
$214.00
$316.00
$418.00
7
(1)

Decitabine, similar to 5-Azacytidine, may impact BANF proteins indirectly through DNA methylation changes.

MS-275

209783-80-2sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$24.00
$88.00
$208.00
24
(2)

MS-275, a selective histone deacetylase inhibitor, potentially affects BANF proteins by modulating chromatin dynamics.

Romidepsin

128517-07-7sc-364603
sc-364603A
1 mg
5 mg
$214.00
$622.00
1
(1)

Romidepsin, a cyclic peptide histone deacetylase inhibitor, could influence BANF proteins by altering chromatin architecture.

Panobinostat

404950-80-7sc-208148
10 mg
$196.00
9
(1)

Panobinostat, a potent histone deacetylase inhibitor, may indirectly impact BANF family proteins through epigenetic mechanisms.

Belinostat

414864-00-9sc-269851
sc-269851A
10 mg
100 mg
$153.00
$561.00
(1)

Belinostat, a histone deacetylase inhibitor, might affect the function of BANF proteins via chromatin remodeling.