ATF-7IP inhibitors belong to a distinct chemical class that plays a pivotal role in modulating cellular processes by targeting ATF-7IP, a crucial transcription factor associated with gene regulation. ATF-7IP, also known as activating transcription factor 7-interacting protein, is involved in chromatin remodeling and transcriptional control, influencing the expression of genes implicated in diverse cellular functions. The inhibitors designed to interact with ATF-7IP act as specific molecular entities capable of binding to its active sites, thereby altering its activity and subsequent downstream effects on gene expression.
ATF-7IP inhibitors is meticulously engineered to ensure high selectivity and affinity for ATF-7IP, minimizing off-target effects. Typically, these compounds possess specific functional groups that facilitate interaction with key residues in the ATF-7IP binding pocket. The development of ATF-7IP inhibitors has been driven by a profound understanding of the structural and biochemical characteristics of ATF-7IP, enabling rational drug design to achieve optimal binding and modulation. As researchers delve into the intricacies of ATF-7IP inhibition, advancements in medicinal chemistry continue to refine the chemical class, enhancing its potency and specificity. The study of ATF-7IP inhibitors represents a promising avenue in deciphering the complexities of gene regulation and chromatin dynamics, offering insights into the fundamental mechanisms governing cellular processes and providing a foundation for further exploration in the realm of molecular biology.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Staurosporine | 62996-74-1 | sc-3510 sc-3510A sc-3510B | 100 µg 1 mg 5 mg | $82.00 $153.00 $396.00 | 113 | |
Staurosporine is a potent protein kinase inhibitor, can indirectly inhibit ATF-7IP by inhibiting protein kinases which are upstream in the signaling pathway. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a potent inhibitor of PI3K, can indirectly inhibit ATF-7IP by blocking the PI3K/Akt signaling pathway. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 is an MEK inhibitor, it can inhibit ATF-7IP by blocking the MAPK/ERK pathway. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a JNK inhibitor, it can inhibit ATF-7IP by affecting the JNK signaling pathway. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin is a flavonoid that inhibits PI3K, it can indirectly inhibit ATF-7IP by affecting the PI3K/Akt pathway. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Rapamycin is an mTOR inhibitor, it can indirectly inhibit ATF-7IP by blocking the mTOR signaling pathway. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Wortmannin is a covalent inhibitor of PI3K, it can inhibit ATF-7IP by blocking the PI3K/Akt pathway. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is an MEK inhibitor, it can indirectly inhibit ATF-7IP by blocking the MAPK/ERK pathway. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a tyrosine kinase inhibitor, it can inhibit ATF-7IP by inhibiting tyrosine kinases that are upstream in the signaling pathway. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 is a p38 MAPK inhibitor, it can inhibit ATF-7IP by blocking the p38 MAPK pathway. | ||||||