ARMC3 inhibitors are a class of chemical compounds that specifically target and modulate the activity of the ARMC3 protein. ARMC3 (Armadillo Repeat Containing 3) is a protein belonging to the armadillo repeat family, known for playing a role in various cellular processes, including signaling pathways, cell structure organization, and protein-protein interactions. These inhibitors are designed to bind to key regions of the ARMC3 protein, potentially altering its structure or preventing its normal interactions with other proteins or cellular components. By modulating ARMC3 activity, these compounds allow researchers to study the functional role of ARMC3 in different biological systems, which could include aspects such as cell cycle regulation, cell adhesion, or intracellular signaling.
ARMC3 inhibitors are diverse, encompassing different structural scaffolds and functional groups that enable specific interactions with the ARMC3 protein. These inhibitors are often identified and optimized through high-throughput screening techniques, followed by structural analysis to improve binding affinity and selectivity for ARMC3. Researchers may utilize various biophysical and biochemical methods, such as crystallography, nuclear magnetic resonance (NMR), or molecular modeling, to study how these inhibitors interact with the ARMC3 protein at the molecular level. Through these approaches, ARMC3 inhibitors can serve as valuable tools in the exploration of cellular mechanisms and pathways associated with ARMC3, helping to clarify its biological functions and the broader impact of its modulation in complex cellular environments.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Doxorubicin | 23214-92-8 | sc-280681 sc-280681A | 1 mg 5 mg | $176.00 $426.00 | 43 | |
An intercalating agent that can disrupt DNA and RNA synthesis, potentially reducing ARMC3 mRNA transcription. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
A histone deacetylase inhibitor which may alter chromatin structure and affect ARMC3 gene expression. | ||||||
Camptothecin | 7689-03-4 | sc-200871 sc-200871A sc-200871B | 50 mg 250 mg 100 mg | $58.00 $186.00 $94.00 | 21 | |
An inhibitor of DNA topoisomerase I, which could lead to decreased transcription of various genes, including ARMC3. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $275.00 $474.00 $1639.00 $2497.00 $5344.00 | 4 | |
A natural product that inhibits translation and could decrease protein synthesis, including that of ARMC3. | ||||||
Cyclopamine | 4449-51-8 | sc-200929 sc-200929A | 1 mg 5 mg | $94.00 $208.00 | 19 | |
A Hedgehog signaling pathway inhibitor that may indirectly impact ARMC3 expression by altering cellular signaling pathways. | ||||||
Puromycin dihydrochloride | 58-58-2 | sc-108071 sc-108071B sc-108071C sc-108071A | 25 mg 250 mg 1 g 50 mg | $42.00 $214.00 $832.00 $66.00 | 394 | |
An antibiotic that causes premature chain termination during protein synthesis, potentially decreasing levels of ARMC3. | ||||||
Bortezomib | 179324-69-7 | sc-217785 sc-217785A | 2.5 mg 25 mg | $135.00 $1085.00 | 115 | |
A proteasome inhibitor that may increase the levels of misfolded proteins, potentially affecting ARMC3 protein turnover. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
An inhibitor of the sarcoplasmic/endoplasmic reticulum Ca2+ ATPase (SERCA), causing stress that could affect ARMC3 expression. | ||||||
Oligomycin A | 579-13-5 | sc-201551 sc-201551A sc-201551B sc-201551C sc-201551D | 5 mg 25 mg 100 mg 500 mg 1 g | $179.00 $612.00 $1203.00 $5202.00 $9364.00 | 26 | |
An inhibitor of ATP synthase that could create metabolic stress, potentially impacting ARMC3 expression. | ||||||
Tunicamycin | 11089-65-9 | sc-3506A sc-3506 | 5 mg 10 mg | $172.00 $305.00 | 66 | |
An inhibitor of N-linked glycosylation that can cause ER stress and impact the expression of proteins like ARMC3. | ||||||