Date published: 2026-4-24

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ARFGAP1 Activators

ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) is a protein that is part of the GTPase-activating proteins (GAPs) family. It plays a crucial role in membrane trafficking and cytoskeleton dynamics. The direct chemical activators for ARFGAP1 are not well-characterized. However, several compounds may indirectly influence ARFGAP1 function through associated pathways or cellular processes.ARFGAP1 Activators represent a diverse class of chemicals that can influence the function of ARFGAP1. While direct activators of ARFGAP1 are not well-documented, these compounds can indirectly influence the function of ARFGAP1 through their effects on related cellular pathways.

Chemicals such as rapamycin, wiskostatin, brefeldin A, SecinH3, QS11, golgicide A, LG186, Exo2, H89, ML141, ZCL278, and CASIN can potentially influence ARFGAP1 function through their effects on ARFGAP1-related pathways. The effects of these chemicals on ARFGAP1 function are context-dependent and may vary based on the cellular environment and other biochemical parameters.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin can inhibit mTOR, a pathway that interacts with ARFGAP1, potentially influencing its function.

Wiskostatin

253449-04-6sc-204399
sc-204399A
sc-204399B
sc-204399C
1 mg
5 mg
25 mg
50 mg
$49.00
$124.00
$441.00
$828.00
4
(1)

Wiskostatin inhibits the N-WASP-ARF1/ARFGAP1 pathway, potentially influencing ARFGAP1 function.

Brefeldin A

20350-15-6sc-200861C
sc-200861
sc-200861A
sc-200861B
1 mg
5 mg
25 mg
100 mg
$31.00
$53.00
$124.00
$374.00
25
(3)

Brefeldin A disrupts ARF1 activity which ARFGAP1 interacts with, potentially influencing its function.

eIF4E/eIF4G Interaction Inhibitor, 4EGI-1

315706-13-9sc-202597
10 mg
$265.00
14
(1)

SecinH3 inhibits human ARF-GEP100, a guanine nucleotide exchange protein that interacts with ARFGAP1, potentially influencing its function.

BI 78D3

883065-90-5sc-203840
sc-203840A
10 mg
50 mg
$204.00
$810.00
2
(1)

QS11 is an inhibitor of AGAP2, an Arf GAP, potentially influencing ARFGAP1 function.

Q-VD-OPH

1135695-98-5sc-222230
5 mg
$782.00
5
(1)

Golgicide A inhibits ARF1, which ARFGAP1 interacts with, potentially impacting its function.

H-89 dihydrochloride

130964-39-5sc-3537
sc-3537A
1 mg
10 mg
$94.00
$186.00
71
(2)

H89 is a protein kinase A inhibitor, and PKA regulates ARF proteins that ARFGAP1 interacts with, potentially influencing its function.

ML 141

71203-35-5sc-362768
sc-362768A
5 mg
25 mg
$137.00
$512.00
7
(1)

ML141 is a potent, selective, reversible, and cell-permeable inhibitor of Cdc42 GTPase, potentially influencing ARFGAP1 function.

ZLN005

49671-76-3sc-474381A
sc-474381
sc-474381B
sc-474381C
5 mg
10 mg
25 mg
50 mg
$45.00
$114.00
$159.00
$262.00
(0)

ZCL278 is a selective Cdc42 GTPase inhibitor, potentially influencing ARFGAP1 function.

CASIN

425399-05-9sc-397016
10 mg
$460.00
1
(0)

CASIN is a selective inhibitor of Cdc42 GTPase, potentially influencing ARFGAP1 function.