ANKRD56 activators are chemicals that can modulate various signaling pathways and cellular processes involving the ANKRD56 protein. Since there is limited information regarding the direct pathways in which ANKRD56 is involved, the proposed activators target known signaling cascades and modifications that could impact a wide range of proteins, including those associated with the ankyrin repeat domain-containing family. These activators include agents that affect second messengers such as cAMP, protein kinase activity, intracellular calcium levels, phosphorylation status, proteasomal degradation, and transcriptional regulation through histone modification. The diversity of these activators reflects the complexity of cellular signaling and the multiple points at which the activity of a protein such as ANKRD56 can be influenced.
The chemicals listed above are recognized for their roles in altering the cellular environment in ways that lead to the modulation of protein functions. For example, activators like Forskolin and Ionomycin elevate intracellular levels of cAMP and calcium, respectively, which can trigger downstream effects on protein kinases that are pivotal in protein interaction networks. Inhibitors of protein phosphatases and kinases such as Calyculin A, SB203580, and LY294002 have been implicated in altering the phosphorylation landscape within the cell, thereby impacting signaling pathways and affecting the function or interaction of ANKRD56 with other proteins.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin activates adenylyl cyclase, leading to increased levels of cAMP, which can promote the activation of PKA and downstream proteins that could interact with ANKRD56. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates protein kinase C (PKC), which can phosphorylate a myriad of proteins, potentially affecting proteins that interact with ANKRD56. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin increases intracellular calcium levels, which may activate calcium-dependent proteins and signaling cascades that might influence ANKRD56 activity. | ||||||
Calyculin A | 101932-71-2 | sc-24000 sc-24000A | 10 µg 100 µg | $163.00 $800.00 | 59 | |
Calyculin A inhibits protein phosphatases 1 (PP1) and 2A (PP2A), which could alter the phosphorylation status of proteins that interact with or regulate ANKRD56. | ||||||
MG-132 [Z-Leu- Leu-Leu-CHO] | 133407-82-6 | sc-201270 sc-201270A sc-201270B | 5 mg 25 mg 100 mg | $60.00 $265.00 $1000.00 | 163 | |
MG132 inhibits the proteasome, potentially increasing the levels of proteins that could interact with or regulate ANKRD56. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $90.00 $349.00 | 284 | |
SB203580 inhibits p38 MAPK, potentially affecting downstream proteins that might modulate the activity or stability of ANKRD56. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 inhibits PI3K, potentially affecting AKT signaling and possibly influencing proteins that associate with ANKRD56. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
PD98059 inhibits MEK, which may affect ERK signaling and could potentially modulate proteins that interact with ANKRD56. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 inhibits JNK, which could affect AP-1 transcription factor activity and potentially impact the expression of genes encoding proteins that interact with ANKRD56. | ||||||
AICAR | 2627-69-2 | sc-200659 sc-200659A sc-200659B | 50 mg 250 mg 1 g | $65.00 $280.00 $400.00 | 48 | |
AICAR activates AMPK, which can influence various metabolic pathways and potentially affect proteins that regulate ANKRD56. | ||||||