ANKRD56 Inhibitors
The class of chemicals known as ANKRD56 Inhibitors are compounds that indirectly target the processes in which ANKRD56 is involved, especially those related to spindle assembly during mitosis. These compounds often target the microtubules, their associated proteins, or kinases that regulate spindle assembly and dynamics. Microtubules are essential components of the mitotic spindle, and their dynamics are crucial for correct chromosome segregation. By targeting these components, the chemicals can influence the function of proteins, such as ANKRD56, which are associated with spindle assembly and chromosome segregation.
For instance, paclitaxel stabilizes microtubules, hindering their dynamic instability, a process vital for spindle assembly and chromosome segregation. Similarly, vinblastine, nocodazole, and colchicine, disrupt microtubule dynamics by binding to tubulin and either inhibiting or promoting its polymerization. On the other hand, inhibitors like monastrol and S-Trityl-L-cysteine target kinesins, motor proteins crucial for proper spindle assembly.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules by binding to the β-tubulin subunit, hindering spindle disassembly. This can indirectly affect the role of ANKRD56 in spindle assembly. | ||||||
Vinblastine | 865-21-4 | sc-491749 sc-491749A sc-491749B sc-491749C sc-491749D | 10 mg 50 mg 100 mg 500 mg 1 g | $102.00 $235.00 $459.00 $1749.00 $2958.00 | 4 | |
Binds to tubulin, inhibiting microtubule assembly, potentially interfering with ANKRD56-related spindle dynamics. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule dynamics by binding to β-tubulin. Can indirectly modulate ANKRD56's function in spindle assembly. | ||||||
Colchicine | 64-86-8 | sc-203005 sc-203005A sc-203005B sc-203005C sc-203005D sc-203005E | 1 g 5 g 50 g 100 g 500 g 1 kg | $100.00 $321.00 $2289.00 $4484.00 $18207.00 $34749.00 | 3 | |
Binds to tubulin, hindering its polymerization into microtubules, which can indirectly influence ANKRD56's role in spindle assembly. | ||||||
Podophyllotoxin | 518-28-5 | sc-204853 | 100 mg | $84.00 | 1 | |
Binds to tubulin, blocking its assembly into microtubules, which might impact ANKRD56-associated spindle formation. | ||||||
Monastrol | 254753-54-3 | sc-202710 sc-202710A | 1 mg 5 mg | $120.00 $233.00 | 10 | |
Inhibits the kinesin Eg5, which is crucial for bipolar spindle formation, potentially affecting ANKRD56's function in this process. | ||||||
Combrestatin A4 | 117048-59-6 | sc-204697 sc-204697A | 1 mg 5 mg | $46.00 $81.00 | ||
Tubulin binding agent that disrupts microtubule formation, potentially affecting ANKRD56's role in spindle formation. | ||||||
BI 2536 | 755038-02-9 | sc-364431 sc-364431A | 5 mg 50 mg | $151.00 $525.00 | 8 | |
Plk1 inhibitor, affecting proper spindle formation and chromosome segregation, indirectly influencing the function of ANKRD56 in spindle assembly. | ||||||
ZM-447439 | 331771-20-1 | sc-200696 sc-200696A | 1 mg 10 mg | $153.00 $356.00 | 15 | |
Aurora kinase inhibitor, affecting spindle checkpoint functions, potentially modulating ANKRD56's role in mitosis. | ||||||
S-Trityl-L-cysteine | 2799-07-7 | sc-202799 sc-202799A | 1 g 5 g | $32.00 $66.00 | 6 | |
Inhibits Eg5, a kinesin involved in centrosome separation, which can indirectly influence ANKRD56's function in spindle assembly. | ||||||