The chemical class known as ANKRD30B Activators encompasses a broad range of compounds that can influence the expression and function of the ANKRD30B protein. These activators are not a homogenous group; rather, they consist of various molecules that can impact signaling pathways, gene expression, and epigenetic modifications. The primary action of these chemicals is to initiate a cascade of cellular events that can lead to the upregulation or enhanced activity of ANKRD30B. These actions include the activation of enzymes that generate secondary messengers, modulation of transcription factor activities, and alteration of the chromatin state to favor gene expression. For instance, some activators within this class function by increasing intracellular levels of secondary messengers such as cyclic AMP, which in turn can activate specific transcription factors. Others can interact directly with components of the transcription machinery or epigenetic modulators, changing the accessibility of the ANKRD30B gene for transcription.
Furthermore, this class includes inhibitors that can indirectly cause the activation of ANKRD30B by blocking negative regulatory pathways. By inhibiting certain kinases or signaling molecules, these chemicals can remove inhibitory signals that would otherwise suppress ANKRD30B expression or activity. The interplay of these activators with various signaling networks within the cell underscores the complex nature of cellular regulation. It's important to recognize that while these chemicals can elicit changes in ANKRD30B activity, their influence extends to multiple cellular targets and processes. This underscores the intricate web of cell signaling and the multifaceted roles that these activators play within the cell. The study and categorization of these activators are vital, as they offer insights into the regulation of proteins that contain ankyrin repeat domains and how these proteins can be modulated within the cellular environment.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $76.00 $150.00 $725.00 $1385.00 $2050.00 | 73 | |
Adenylyl cyclase activator, increases cAMP levels, which could activate the cAMP response element-binding protein (CREB), potentially enhancing transcription of genes including ANKRD30B. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $40.00 $129.00 $210.00 $490.00 $929.00 | 119 | |
Protein kinase C (PKC) activator, which could modulate signaling pathways, leading to the activation of transcription factors that could increase ANKRD30B transcription. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
Histone deacetylase inhibitor (HDACi) that could alter chromatin structure and activate transcription of various genes, possibly including ANKRD30B by making its promoter more accessible. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
DNA methyltransferase inhibitor that could demethylate DNA and activate gene expression, potentially affecting genes silenced by methylation including ANKRD30B. | ||||||
SB 202190 | 152121-30-7 | sc-202334 sc-202334A sc-202334B | 1 mg 5 mg 25 mg | $30.00 $125.00 $445.00 | 45 | |
p38 MAPK inhibitor that, by inhibiting p38 MAPK, could shift the equilibrium in signaling pathways and could activate the expression of stress response genes like ANKRD30B. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
PI3K inhibitor that could affect the PI3K/Akt pathway, altering the transcription of various genes through effects on downstream targets, potentially including ANKRD30B. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A compound from turmeric that could modulate multiple signaling pathways, including NF-kB, which may affect the expression of ANKRD30B. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
SIRT1 activator that could impact gene expression through deacetylation of histones and transcription factors, possibly altering ANKRD30B expression levels. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor that could modify the JNK signaling pathway, potentially affecting transcription factors that regulate ANKRD30B gene expression. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
MEK inhibitor that could affect the MAPK/ERK pathway, and thereby potentially modulate the expression of genes including ANKRD30B. |