ANKRD11 Inhibitors
ANKRD11 inhibitors are chemical compounds that modulate the activity of ANKRD11, which stands for Ankyrin Repeat Domain 11. ANKRD11 is a protein with a role in chromatin remodeling and transcriptional regulation, and it is a member of a family of proteins characterized by ankyrin repeat domains, which are structural motifs involved in protein-protein interactions. ANKRD11 is known to play a role in various developmental processes and may have implications in neurodevelopmental disorders.
ANKRD11 inhibitors exert their effects by interfering with the function or expression of ANKRD11, disrupting its role in chromatin remodeling and transcriptional regulation. This interference can lead to alterations in gene expression patterns and cellular processes governed by ANKRD11, influencing development and other biological functions. Researchers employ ANKRD11 inhibitors as valuable tools to investigate the specific roles of ANKRD11 in different cellular contexts, particularly during development, and to gain insights into the molecular mechanisms underlying gene regulation and its relevance to genetic disorders.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
A histone deacetylase inhibitor that may cause broad changes in gene expression, potentially affecting ANKRD11 levels. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $218.00 $322.00 $426.00 | 7 | |
A DNA methyltransferase inhibitor, altering DNA methylation patterns and potentially downregulating ANKRD11 expression. | ||||||
Suberoylanilide Hydroxamic Acid | 149647-78-9 | sc-220139 sc-220139A | 100 mg 500 mg | $133.00 $275.00 | 37 | |
Another HDAC inhibitor that leads to altered chromatin structure and could influence ANKRD11 expression. | ||||||
RG 108 | 48208-26-0 | sc-204235 sc-204235A | 10 mg 50 mg | $131.00 $515.00 | 2 | |
A non-nucleoside DNA methyltransferase inhibitor that may indirectly reduce ANKRD11 expression by changing the epigenetic landscape. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $55.00 | 6 | |
A compound that binds to DNA and could potentially downregulate genes like ANKRD11. | ||||||
MS-275 | 209783-80-2 | sc-279455 sc-279455A sc-279455B | 1 mg 5 mg 25 mg | $24.00 $90.00 $212.00 | 24 | |
Selectively inhibits class I HDACs which could affect ANKRD11 expression as part of global gene expression changes. | ||||||
Romidepsin | 128517-07-7 | sc-364603 sc-364603A | 1 mg 5 mg | $218.00 $634.00 | 1 | |
A potent HDAC inhibitor that could alter the expression of genes involved in development and neural function. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As an HDAC inhibitor, it may change the acetylation status of histones at the ANKRD11 locus, affecting its expression. | ||||||
Panobinostat | 404950-80-7 | sc-208148 | 10 mg | $200.00 | 9 | |
A broad-range HDAC inhibitor that could potentially downregulate ANKRD11 through global histone acetylation changes. | ||||||
Sirtinol | 410536-97-9 | sc-205976 sc-205976A | 1 mg 5 mg | $38.00 $113.00 | 14 | |
Inhibits sirtuin HDACs, which might modify the expression of genes like ANKRD11. | ||||||