AMZ2 Inhibitors
AMZ2 inhibitors such as the inhibition of kinase activity, interference with receptor-ligand interactions, suppression of specific enzyme functions, and modulation of gene expression. For instance, chemicals like Zafirlukast, SB431542, and DAPT interact with receptor-mediated pathways, such as those mediated by leukotrienes, TGF-beta, and Notch, respectively. These pathways can influence the regulatory networks in which a protein like AMZ2 operates.
On the other hand, compounds like Manumycin A, LY294002, PD 98059, SP600125, U0126, Wortmannin, and Rapamycin target various kinases or kinase pathways such as Ras, PI3K/Akt, MAPK/ERK, JNK, and mTOR. By inhibiting these kinases, the chemicals can impede the phosphorylation events that are essential for the propagation of signals within the cell, thus affecting the activity of AMZ2. In addition to these, chemicals that influence other cellular processes, such as Apocynin and NS-398, exert effects on the generation of reactive oxygen species and the synthesis of prostaglandins, respectively. These processes are closely related to cell signaling and can have an impact on the functional state of proteins that are analogous to AMZ2.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Zafirlukast | 107753-78-6 | sc-204942 sc-204942A | 10 mg 100 mg | $37.00 $174.00 | 1 | |
Antagonist of the cysteinyl leukotriene receptor 1, can downregulate inflammatory pathways that may modulate the activity of proteins similar to AMZ2. | ||||||
Manumycin A | 52665-74-4 | sc-200857 sc-200857A | 1 mg 5 mg | $219.00 $634.00 | 5 | |
Inhibitor of Ras farnesyltransferase, can affect Ras signaling and thereby modulate the activity of proteins in the same pathway as AMZ2. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $82.00 $216.00 $416.00 | 48 | |
Inhibitor of the TGF-beta receptor, can alter the TGF-beta signaling pathway, affecting the regulation of proteins like AMZ2. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
Inhibitor of PI3K, can attenuate the PI3K/Akt signaling pathway affecting proteins downstream or within the same pathway as AMZ2. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $40.00 $92.00 | 212 | |
MEK inhibitor, can interfere with the MAPK/ERK pathway, potentially modulating proteins involved in the same signaling cascade as AMZ2. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
JNK inhibitor, can affect the JNK signaling pathway, which may regulate the activity of proteins like AMZ2. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
mTOR inhibitor, can downregulate the mTOR signaling pathway, which could modulate the activity of proteins in the same pathway as AMZ2. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
PI3K inhibitor, can suppress the PI3K/Akt pathway, influencing the regulation of proteins within the same pathway as AMZ2. | ||||||
Apocynin | 498-02-2 | sc-203321 sc-203321A sc-203321B sc-203321C | 1 g 10 g 100 g 500 g | $27.00 $68.00 $116.00 $360.00 | 74 | |
NADPH oxidase inhibitor, can reduce reactive oxygen species production, which may affect the signaling pathways involving proteins like AMZ2. | ||||||
NS-398 | 123653-11-2 | sc-200604 sc-200604A | 5 mg 25 mg | $86.00 $339.00 | 9 | |
COX-2 inhibitor, can attenuate prostaglandin synthesis, potentially influencing the activity of proteins associated with AMZ2. | ||||||