ALG14 Activators represent a specialized class of chemical compounds or molecules that have garnered attention within the field of molecular biology and cellular research. These activators are designed or discovered with the specific aim of modulating the activity of the ALG14 gene. ALG14, or Asparagine-Linked Glycosylation 14 Homolog, is a protein-coding gene found in humans and various organisms. It plays a crucial role in the process of asparagine-linked glycosylation (N-glycosylation), a post-translational modification of proteins that involves the attachment of complex sugar molecules to specific amino acid residues.
The study of ALG14 activators is of significant interest because it allows researchers to delve into the precise role of the ALG14 gene in cellular physiology and molecular mechanisms related to protein glycosylation. Activation of ALG14 can offer valuable insights into its potential involvement in the complex machinery responsible for modifying proteins with N-linked glycans, a process essential for proper protein folding, stability, and function. By manipulating the activity of ALG14 through these activators, scientists aim to gain a deeper understanding of the intricate molecular pathways and cellular functions that rely on the gene product, thereby contributing to the broader knowledge of gene regulation and cellular behavior. Consequently, ALG14 activators serve as valuable tools for researchers dedicated to unraveling the detailed molecular mechanisms that govern cellular biology, particularly in the context of protein glycosylation and its significance in cellular processes.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
Curcumin may affect transcription factor activity, which in turn could hypothetically lead to increased ALG14 expression. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $60.00 $185.00 $365.00 | 64 | |
Resveratrol is known to influence gene expression and may hypothetically enhance ALG14 transcription. | ||||||
D,L-Sulforaphane | 4478-93-7 | sc-207495A sc-207495B sc-207495C sc-207495 sc-207495E sc-207495D | 5 mg 10 mg 25 mg 1 g 10 g 250 mg | $150.00 $286.00 $479.00 $1299.00 $8299.00 $915.00 | 22 | |
As an HDAC inhibitor, sulforaphane could potentially increase histone acetylation and promote ALG14 expression. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $26.00 $92.00 $120.00 $310.00 $500.00 $908.00 $1821.00 | 46 | |
Genistein, a tyrosine kinase inhibitor, might influence transcription factors and putatively upregulate ALG14 expression. | ||||||
Flavopiridol | 146426-40-6 | sc-202157 sc-202157A | 5 mg 25 mg | $78.00 $254.00 | 41 | |
Flavopiridol inhibits cyclin-dependent kinases, potentially altering transcription regulation and possibly increasing ALG14 levels. | ||||||
Histone Lysine Methyltransferase Inhibitor Inhibitor | 935693-62-2 free base | sc-202651 | 5 mg | $148.00 | 4 | |
BIX-01294, an inhibitor of G9a methyltransferase, might lead to chromatin remodeling and hypothetically affect ALG14 expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $108.00 $245.00 $918.00 $49.00 | 33 | |
Quercetin may modulate signaling pathways and transcription factors, which could hypothetically result in ALG14 induction. | ||||||
Metformin | 657-24-9 | sc-507370 | 10 mg | $77.00 | 2 | |
Metformin activates AMPK, which may lead to transcriptional changes, potentially impacting ALG14 expression. | ||||||
Pioglitazone | 111025-46-8 | sc-202289 sc-202289A | 1 mg 5 mg | $54.00 $123.00 | 13 | |
It is a PPAR-gamma agonist which might indirectly influence gene expression and perhaps enhance ALG14 transcription. | ||||||
Phenethyl isothiocyanate | 2257-09-2 | sc-205801 sc-205801A | 5 g 10 g | $102.00 $179.00 | 2 | |
As an HDAC inhibitor, it might increase acetylation levels, potentially resulting in the upregulation of ALG14. |