ACOT7 inhibitors belong to a specific category of chemical compounds designed to target and inhibit the activity of the ACOT7 protein, also known as Acyl-CoA Thioesterase 7. ACOT7 is an enzyme that plays a crucial role in lipid metabolism within cells. It is primarily involved in the hydrolysis of acyl-CoA molecules, which are essential intermediates in various metabolic pathways, including fatty acid oxidation and lipid biosynthesis. By catalyzing the breakdown of acyl-CoA compounds, ACOT7 regulates the availability of fatty acids for energy production or lipid synthesis, making it a key player in cellular lipid homeostasis. Inhibitors of ACOT7 are primarily developed for research purposes, serving as valuable tools for scientists and researchers to investigate the molecular mechanisms and functions associated with this enzyme in the context of lipid metabolism.
ACOT7 inhibitors are typically composed of small molecules or chemical compounds specifically designed to interact with the ACOT7 protein, disrupting its normal enzymatic activity. By inhibiting ACOT7, these compounds can potentially impact the balance of acyl-CoA molecules within cells, influencing various lipid-related processes. Researchers use ACOT7 inhibitors in laboratory settings to manipulate the activity of this enzyme and study its roles in cellular lipid metabolism, energy production, and lipid storage. These inhibitors provide valuable insights into the molecular mechanisms by which ACOT7 influences lipid homeostasis and contribute to a deeper understanding of its significance in the context of cellular biology. While ACOT7 inhibitors may have broader implications, their primary purpose is to assist scientists in deciphering the intricacies of ACOT7-mediated lipid metabolism.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $149.00 $470.00 $620.00 $1199.00 $2090.00 | 33 | |
An inhibitor of histone deacetylase which could result in altered histone acetylation levels, potentially affecting ACOT7 gene expression. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
A DNA methyltransferase inhibitor that can cause hypomethylation of DNA, possibly leading to changes in ACOT7 expression. | ||||||
Mithramycin A | 18378-89-7 | sc-200909 | 1 mg | $54.00 | 6 | |
Can bind to GC-rich DNA sequences, potentially preventing the binding of transcription factors to the ACOT7 promoter region. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $88.00 $200.00 | 13 | |
Known for its broad transcriptional repression properties, which could nonspecifically decrease ACOT7 mRNA levels. | ||||||
Chloroquine | 54-05-7 | sc-507304 | 250 mg | $68.00 | 2 | |
By intercalating into DNA, chloroquine can affect DNA replication and transcription, potentially altering ACOT7 mRNA synthesis. | ||||||
α-Amanitin | 23109-05-9 | sc-202440 sc-202440A | 1 mg 5 mg | $260.00 $1029.00 | 26 | |
Specifically targets RNA polymerase II and inhibits mRNA synthesis, which may reduce transcription of the ACOT7 gene. | ||||||
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $73.00 $238.00 $717.00 $2522.00 $21420.00 | 53 | |
Intercalates into DNA and inhibits RNA polymerase activity, potentially reducing transcription of ACOT7. | ||||||
5-Aza-2′-Deoxycytidine | 2353-33-5 | sc-202424 sc-202424A sc-202424B | 25 mg 100 mg 250 mg | $214.00 $316.00 $418.00 | 7 | |
A hypomethylating agent that might affect the epigenetic regulation of genes, possibly altering the expression of ACOT7. | ||||||
Rocaglamide | 84573-16-0 | sc-203241 sc-203241A sc-203241B sc-203241C sc-203241D | 100 µg 1 mg 5 mg 10 mg 25 mg | $270.00 $465.00 $1607.00 $2448.00 $5239.00 | 4 | |
Inhibits translation initiation and could therefore decrease protein levels, potentially affecting ACOT7 synthesis. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
An mTOR inhibitor which can affect the translation of mRNA, potentially decreasing the production of ACOT7. |