ABCD1 Inhibitors
ABCD1 inhibitors belong to a specific chemical class that primarily focuses on their interaction with the ABCD1 protein. This class of compounds is characterized by their ability to modulate the activity of the ABCD1 protein, which is integral to cellular processes. ABCD1, found in the membrane of certain cell organelles, plays a pivotal role in the transport of very-long-chain fatty acids (VLCFAs) into these compartments. ABCD1 inhibitors are designed to interact with the active site of the ABCD1 protein, altering its functionality and subsequently influencing the transport of VLCFAs.
These inhibitors typically feature a distinct molecular structure that enables them to bind to specific sites on the protein's surface. The interaction between the inhibitors and the ABCD1 protein can result in changes to its conformation or impede its normal transport function. The ultimate impact of ABCD1 inhibitors on cellular processes is an area of scientific investigation and may have implications in various contexts beyond their direct chemical interactions.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Lovastatin | 75330-75-5 | sc-200850 sc-200850A sc-200850B | 5 mg 25 mg 100 mg | $28.00 $88.00 $332.00 | 12 | |
Inhibits cholesterol synthesis, indirectly affecting ABCD1 function by modulating cellular lipid composition and trafficking. | ||||||
Gemfibrozil | 25812-30-0 | sc-204764 sc-204764A | 5 g 25 g | $65.00 $262.00 | 2 | |
Modulates peroxisome proliferator-activated receptors (PPARs), indirectly influencing ABCD1 activity and fatty acid metabolism. | ||||||
Bezafibrate | 41859-67-0 | sc-204650B sc-204650 sc-204650A sc-204650C | 500 mg 1 g 5 g 10 g | $30.00 $45.00 $120.00 $200.00 | 5 | |
Acts as a PPAR agonist, impacting lipid metabolism and potentially influencing ABCD1 expression and function. | ||||||
Simvastatin | 79902-63-9 | sc-200829 sc-200829A sc-200829B sc-200829C | 50 mg 250 mg 1 g 5 g | $30.00 $87.00 $132.00 $434.00 | 13 | |
Inhibits HMG-CoA reductase, leading to altered cholesterol levels and potential secondary effects on ABCD1 activity. | ||||||
GW6471 | 880635-03-0 | sc-300779 | 5 mg | $289.00 | 9 | |
Antagonizes PPARα activity, potentially influencing lipid homeostasis and ABCD1-related processes. | ||||||
Pravastatin | 81093-37-0 | sc-222188 | 50 mg | $400.00 | 1 | |
HMG-CoA reductase inhibitor, affecting cholesterol levels and indirectly influencing ABCD1 function through lipid alterations. | ||||||
Fenofibrate | 49562-28-9 | sc-204751 | 5 g | $40.00 | 9 | |
PPARα agonist, impacting lipid metabolism and potentially affecting ABCD1 expression and peroxisomal processes. | ||||||
Ciprofibrate | 52214-84-3 | sc-204689 sc-204689A | 25 mg 100 mg | $57.00 $169.00 | ||
Activates PPARα, potentially influencing lipid metabolism and cellular processes linked to ABCD1 activity. | ||||||
Clofibrate | 637-07-0 | sc-200721 | 1 g | $32.00 | ||
Acts on PPARα, impacting lipid metabolism and potentially having downstream effects on ABCD1 function and peroxisomal processes. | ||||||
WY 14643 | 50892-23-4 | sc-203314 | 50 mg | $133.00 | 7 | |
PPARα agonist, affecting lipid homeostasis and potentially influencing ABCD1-related peroxisomal functions. | ||||||