AASS Activators
AASS Activators are chemical compounds that enhance the functional activity of AASS, a crucial enzyme in lysine metabolism. These activators primarily function by providing substrates for the enzymatic reactions that AASS catalyzes, thereby enhancing AASS's activity. The chosen AASS activators include intermediates of the Krebs cycle such as α-Ketoglutarate, Fumarate, Succinate, Citrate, Isocitrate, Malate, Oxaloacetate, and other key molecules in cellular metabolism like Pyruvate, Acetyl-CoA, Glutamate, and Aspartate. By providing these substrates, these activators enhance AASS's role in lysine degradation.
Nicotinamide, another chosen activator, works differently by acting as a precursor in the synthesis of NAD+, a cofactor for AASS. By increasing the availability of NAD+, Nicotinamide can enhance the enzymatic activity of AASS. The other activators, like Pyruvate, Glutamate, and Aspartate, function by providing substrates for the transamination reactions that AASS catalyzes. Thus, all these AASS activators enhance the enzyme's functional activity through their role in providing substrates and cofactor necessary for the enzyme's metabolic reactions.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
α-Ketoglutaric Acid | 328-50-7 | sc-208504 sc-208504A sc-208504B sc-208504C sc-208504D sc-208504E sc-208504F | 25 g 100 g 250 g 500 g 1 kg 5 kg 16 kg | $33.00 $43.00 $63.00 $110.00 $188.00 $738.00 $2091.00 | 2 | |
α-Ketoglutarate is an intermediate in the Krebs cycle. As AASS is involved in lysine metabolism, α-Ketoglutarate can enhance AASS activity by providing substrate for the lysine degradation pathway. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Nicotinamide is a form of vitamin B3 that acts as a precursor in the synthesis of NAD+, which is a cofactor for AASS. By providing more NAD+, Nicotinamide can enhance the enzymatic activity of AASS. | ||||||
Fumaric acid | 110-17-8 | sc-250031 sc-250031A sc-250031B sc-250031C | 25 g 100 g 500 g 2.5 kg | $43.00 $57.00 $114.00 $228.00 | ||
Fumarate is an intermediate in the Krebs cycle. As AASS is involved in lysine metabolism, Fumarate can enhance AASS activity by providing substrate for the lysine degradation pathway. | ||||||
Succinic acid | 110-15-6 | sc-212961B sc-212961 sc-212961A | 25 g 500 g 1 kg | $45.00 $75.00 $133.00 | ||
Succinate is an intermediate in the Krebs cycle. As AASS is involved in lysine metabolism, Succinate can enhance AASS activity by providing substrate for the lysine degradation pathway. | ||||||
Citric Acid, Anhydrous | 77-92-9 | sc-211113 sc-211113A sc-211113B sc-211113C sc-211113D | 500 g 1 kg 5 kg 10 kg 25 kg | $50.00 $110.00 $145.00 $248.00 $598.00 | 1 | |
Citrate is an intermediate in the Krebs cycle. As AASS is involved in lysine metabolism, Citrate can enhance AASS activity by providing substrate for the lysine degradation pathway. | ||||||
Malic acid | 6915-15-7 | sc-257687 | 100 g | $130.00 | 2 | |
Malate is an intermediate in the Krebs cycle. As AASS is involved in lysine metabolism, Malate can enhance AASS activity by providing substrate for the lysine degradation pathway. | ||||||
Oxaloacetic Acid | 328-42-7 | sc-279934 sc-279934A sc-279934B | 25 g 100 g 1 kg | $306.00 $963.00 $7980.00 | 1 | |
Oxaloacetate is an intermediate in the Krebs cycle. As AASS is involved in lysine metabolism, Oxaloacetate can enhance AASS activity by providing substrate for the lysine degradation pathway. | ||||||
Acetyl coenzyme A trisodium salt | 102029-73-2 | sc-210745 sc-210745A sc-210745B | 1 mg 5 mg 1 g | $47.00 $92.00 $5826.00 | 3 | |
Acetyl-CoA is a key molecule in metabolism, used in many biochemical reactions. As AASS is involved in lysine metabolism, Acetyl-CoA can enhance AASS activity by providing substrate for the lysine degradation pathway. | ||||||
L-Glutamic Acid | 56-86-0 | sc-394004 sc-394004A | 10 g 100 g | $297.00 $577.00 | ||
Glutamate is a key molecule in cellular metabolism. As AASS is involved in lysine metabolism, Glutamate can enhance AASS activity by acting as an amino donor in the transamination reactions that AASS catalyzes. | ||||||
L-Aspartic acid | 56-84-8 | sc-472377A sc-472377 sc-472377B | 25 g 100 g 500 g | $40.00 $33.00 $48.00 | ||
Aspartate is a key molecule in cellular metabolism. As AASS is involved in lysine metabolism, Aspartate can enhance AASS activity by acting as an amino donor in the transamination reactions that AASS catalyzes. | ||||||