Date published: 2025-12-4

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Fumaric acid (CAS 110-17-8)

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Alternate Names:
(E)-but-2-enedioic acid
CAS Number:
110-17-8
Purity:
≥99%
Molecular Weight:
116.07
Molecular Formula:
C4H4O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Fumaric acid, a dicarboxylic acid, can be naturally found in various plants, plant-derived products. Its presence is notable in specific fruits, vegetables, and beverages. The applications of fumaric acid span across industrial realms, making it a versatile component. Its utilization extends to numerous laboratory experiments and research endeavors. Scientifically, fumaric acid serves various research purposes. In vitro, fumaric acid is employed to investigate the impacts of environmental stressors on cell cultures. Functionally, fumaric acid acts as an organic acid intermediate within the tricarboxylic acid cycle, also known as the Krebs cycle. This cycle plays a vital role in energy production from glucose. Additionally, fumaric acid participates in the synthesis of lactic acid, succinic acid, and malic acid. Its involvement extends further to the synthesis of other compounds like urea, creatine, and creatinine.


Fumaric acid (CAS 110-17-8) References

  1. Fumaric acid and its esters: an emerging treatment for multiple sclerosis with antioxidative mechanism of action.  |  Gold, R., et al. 2012. Clin Immunol. 142: 44-8. PMID: 21414846
  2. Fumaric acid production in Saccharomyces cerevisiae by simultaneous use of oxidative and reductive routes.  |  Xu, G., et al. 2013. Bioresour Technol. 148: 91-6. PMID: 24045196
  3. Systemic therapy with fumaric acid derivates: new possibilities in the treatment of psoriasis.  |  Nieboer, C., et al. 1989. J Am Acad Dermatol. 20: 601-8. PMID: 2654206
  4. Recent advances in the biomedical applications of fumaric acid and its ester derivatives: The multifaceted alternative therapeutics.  |  Das, RK., et al. 2016. Pharmacol Rep. 68: 404-14. PMID: 26922546
  5. Fumaric acid production using renewable resources from biodiesel and cane sugar production processes.  |  Papadaki, A., et al. 2018. Environ Sci Pollut Res Int. 25: 35960-35970. PMID: 29654455
  6. Bioproduction of fumaric acid: an insight into microbial strain improvement strategies.  |  Sebastian, J., et al. 2019. Crit Rev Biotechnol. 39: 817-834. PMID: 31138023
  7. Use of fumaric acid to control pH and inhibit malolactic fermentation in wines.  |  Morata, A., et al. 2020. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 37: 228-238. PMID: 31697220
  8. Fumaric acid incorporated Ag/agar-agar hybrid hydrogel: A multifunctional avenue to tackle wound healing.  |  Basha, SI., et al. 2020. Mater Sci Eng C Mater Biol Appl. 111: 110743. PMID: 32279739
  9. Fumaric acid protect the cadmium-induced hepatotoxicity in rats: owing to its antioxidant, anti-inflammatory action and aid in recast the liver function.  |  Kaur, G., et al. 2020. Naunyn Schmiedebergs Arch Pharmacol. 393: 1911-1920. PMID: 32440768
  10. Enhancing effect of fumaric acid on transdermal penetration of loxoprofen sodium.  |  Zhang, D., et al. 2020. Int J Pharm. 588: 119722. PMID: 32805639
  11. Evaluation of Fumaric Acid and Maleic Acid as Internal Standards for NMR Analysis of Protein Precipitated Plasma, Serum, and Whole Blood.  |  Nagana Gowda, GA., et al. 2021. Anal Chem. 93: 3233-3240. PMID: 33538164
  12. Fumaric acid production using alternate fermentation mode by immobilized Rhizopus oryzae-a greener production strategy.  |  Sebastian, J., et al. 2021. Chemosphere. 281: 130858. PMID: 34020187
  13. Effect of fumaric acid on the growth of Lactobacillus delbrueckii ssp. bulgaricus during yogurt fermentation.  |  Yamamoto, E., et al. 2021. J Dairy Sci. 104: 9617-9626. PMID: 34099292

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Fumaric acid, 25 g

sc-250031
25 g
$42.00

Fumaric acid, 100 g

sc-250031A
100 g
$56.00

Fumaric acid, 500 g

sc-250031B
500 g
$112.00

Fumaric acid, 2.5 kg

sc-250031C
2.5 kg
$224.00