Molecular structure of Citric Acid, Anhydrous, CAS Number: 77-92-9
Citric Acid, Anhydrous (CAS 77-92-9)
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Alternate Names:
Aciletten
Application:
Citric Acid, Anhydrous is used in the preparation of citrate buffer for antigen and epitope unmasking in IHC
CAS Number:
77-92-9
Purity:
≥98%
Molecular Weight:
192.13
Molecular Formula:
C6H8O7
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Citric Acid is an acidic compound from citrus fruits as a starting point in the Krebs cycle, citrate is a key intermediate in metabolism. Citric acid is one of a series of compounds responsible for the physiological oxidation of fats, carbohydrates and proteins to carbon dioxide and water. Often used to prepare citrate buffer for antigen retrieval of tissue samples. The citrate solution is designed to break protein cross-links thus, unmasking antigens and epitopes in formalin-fixed and paraffin embedded tissue sections, resulting in enhancing staining intensity of antibodies. Citrate has anticoagulant activity as a calcium chelator, it forms complexes that disrupt the tendency of blood to clot. May be used to adjust pH and as a sequestering agent for the removal of trace metals. Additional forms available: Citric Acid Monohydrate (sc-203327) Sodium Citrate, Dihydrate (sc-203383) Citric Acid Trisodium Salt (sc-214745) Sodium citrate monobasic (sc-215869) Sodium citrate tribasic hydrate (sc-236898) Citrate Concentrated Solution (sc-294091)
Citric Acid, Anhydrous (CAS 77-92-9) References
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- Development and validation of an assay for citric acid/citrate and phosphate in pharmaceutical dosage forms using ion chromatography with suppressed conductivity detection. | DeBorba, BM., et al. 2004. J Pharm Biomed Anal. 36: 517-24. PMID: 15522525
- Capsule endoscopy for gastrointestinal bleeding with an obscure etiology. | Chao, CC., et al. 2005. J Formos Med Assoc. 104: 659-65. PMID: 16276441
- Deliquescence-induced caking in binary powder blends. | Salameh, AK. and Taylor, LS. 2006. Pharm Dev Technol. 11: 453-64. PMID: 17101516
- Thrombin activatable fibrinolysis inhibitor (TAFI) in cord blood. | Uszyński, W., et al. 2007. Folia Histochem Cytobiol. 45: 33-6. PMID: 17378243
- Advanced calibration strategy for in situ quantitative monitoring of phase transition processes in suspensions using FT-Raman spectroscopy. | Chen, ZP., et al. 2008. Anal Chem. 80: 6658-65. PMID: 18665607
- Kinetics of moisture-induced hydrolysis in powder blends stored at and below the deliquescence relative humidity: investigation of sucrose-citric acid mixtures. | Kwok, K., et al. 2010. J Agric Food Chem. 58: 11716-24. PMID: 20964346
- Efficient one-pot synthesis of molecularly imprinted silica nanospheres embedded carbon dots for fluorescent dopamine optosensing. | Mao, Y., et al. 2012. Biosens Bioelectron. 38: 55-60. PMID: 22672763
- Down- and up-conversion luminescent carbon dot fluid: inkjet printing and gel glass fabrication. | Wang, F., et al. 2014. Nanoscale. 6: 3818-23. PMID: 24577562
- Whiteness improvement of citric acid crosslinked cotton fabrics: H2O2 bleaching under alkaline condition. | Tang, P., et al. 2016. Carbohydr Polym. 147: 139-145. PMID: 27178918
- Chitosan film incorporated with citric acid and glycerol as an active packaging material for extension of green chilli shelf life. | Priyadarshi, R., et al. 2018. Carbohydr Polym. 195: 329-338. PMID: 29804984
- Nano-oxides washcoat for enhanced catalytic oxidation activity toward the perovskite-based monolithic catalyst. | Lv, C., et al. 2021. Environ Sci Pollut Res Int. 28: 37142-37157. PMID: 33709317
- Antigen retrieval technique utilizing citrate buffer or urea solution for immunohistochemical demonstration of androgen receptor in formalin-fixed paraffin sections. | Shi, SR., et al. 1993. J Histochem Cytochem. 41: 1599-604. PMID: 7691930
- [Value of protein 53 expression in lymphoma. Its correlation with genetic mutations]. | Echezarreta, G., et al. 1997. Sangre (Barc). 42: 369-75. PMID: 9424736
- The effects of microbial phytase, citric acid, and their interaction in a corn-soybean meal-based diet for weanling pigs. | Radcliffe, JS., et al. 1998. J Anim Sci. 76: 1880-6. PMID: 9690644
Inhibitor of:
α-KGD, ACSF1, Citrate Lyase, D2HGDH, galectin-2, L-Asparaginase, Listeria monocytogenes, Nephrocalcin, ODAM, PDH-E1α, PF-4, PGAM4, and SEDL.Activator of:
β-defensin 108B, β-defensin 108C, β-defensin 113, β-defensin 41, β-ketoacyl synthase, β3Gn-T2, δ-FR, ζ-crystallin, AASS, AATM, ACCα, Acetyl-CoA Synthetase, ACO2, ACOT10, ACSS3, Aldolase, Aldolase A, Amylase 2, AOX1, ATP-citrate synthase, BPGM, C10orf65, C330005M16Rik, CDO, Citrate Lyase, CLYBL, COASY, CYBRD1, DHDPSL, DLD, DPM2, ECHS1, EG240549, Enamelin, Enrofloxacin, FAHD1, FAR1, FAR2, Fatso, Fatty Acid Synthase, FIH-1, FUCA1, FUCA2, FucT-X, GK1, GLCNE, GLYAT, GLYATL1, GLYATL3, GLYCTK, GPD1, GPD2, GPR4, IDH3A, IDH3B, IDH3G, IDHC, IscU1, IscU2, JMJD8, LOC283398, LYZL1, MCAT, ME1, ME2, ME3, Med6, METTL2, MIPP, MMD2, muscle FBPase, NaDC-1, NaDC-3, NANS, NIP30, NOL55, Obp1a, OGDHL, OGFOD3, Olfr110, Olfr111, Olfr517, Olfr518, OSGEPL1, OTA, pantophysin, PDPR, PDSS1, Pepsin A3, Pepsin C, PFK-1, PFK-2 tes, Polyethylene Glycol, PPC-DC, RMND1, Salmonella enteriditis 0-9, SDHB, SDHC, SLC13A5, SLC17A4, SLC25A38, SLC48A1, Slc5a11, SOAT1, Statherin, SUCO, T2R26, THNSL1, Urease β, WAP, and ZIP2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Citric Acid, Anhydrous, 500 g | sc-211113 | 500 g | $49.00 | |||
Citric Acid, Anhydrous, 1 kg | sc-211113A | 1 kg | $108.00 | |||
Citric Acid, Anhydrous, 5 kg | sc-211113B | 5 kg | $142.00 | |||
Citric Acid, Anhydrous, 10 kg | sc-211113C | 10 kg | $243.00 | |||
Citric Acid, Anhydrous, 25 kg | sc-211113D | 25 kg | $586.00 |