HDAC Inhibitors

Santa Cruz Biotechnology now offers a broad range of HDAC Inhibitors. Histone deacetylase proteins (HDACs) are a class of enzymes that remove acetyl groups (O=C-CH3) from an <ε>-N-acetyl lysine amino acid on a histone, allowing histones to wrap DNA more tightly. The deacetylation of histones is associated with transcriptional silencing. Histone deacetylase inhibitors (HDIs) have a long history of use in psychiatry and neurology as mood stabilizers and anti-epileptic. HDIs are studied as a treatment for neurodegenerative diseases and have a potential for cancer therapy. HDAC Inhibitors offered by Santa Cruz inhibit HDAC and, in some cases, other chromatin remodeling and transcription regulation related proteins. View detailed HDAC Inhibitor specifications, including HDAC Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
Suberoylanilide Hydroxamic Acid
Suberoylanilide Hydroxamic Acid is a potent HDAC inhibitor; also causes cell cycle arrest at G1
149647-78-9 sc-220139
sc-220139A
100 mg
500 mg
$115.00
$220.00
28
(2)
Sodium phenylbutyrate
Sodium phenylbutyrate is an HDAC inhibitor and caspase activator
1716-12-7 sc-200652
sc-200652A
sc-200652B
sc-200652C
sc-200652D
1 g
10 g
100 g
1 kg
10 kg
$64.00
$150.00
$600.00
$4,800.00
$31,500.00
24
(1)
Panobinostat
Panobinostat is an HDAC inhibitor reported to inhibit human multiple myeloma cell lines
404950-80-7 sc-208148
10 mg
$186.00
5
(1)
PCI-24781
PCI-24781 is an HDAC1, HDAC2, HDAC3, HDAC6, HDAC8, and HDAC10 inhibitor
783355-60-2 sc-364565
sc-364565A
5 mg
50 mg
$150.00
$1,200.00
0
(1)
Luteolin
Luteolin is an inhibitor of LPS-induced TNF-α, IL-6 and inducible nitric oxide production and blocker of NF-κB and AP-1 activation
491-70-3 sc-203119
sc-203119A
sc-203119B
sc-203119C
sc-203119D
5 mg
50 mg
500 mg
5 g
500 g
$20.00
$25.00
$60.00
$80.00
$1,850.00
11
(1)
VAHA
VAHA is an inhibitor to HDAC with efficacy against Class I and II enzymes
106132-78-9 sc-364642
sc-364642A
5 mg
25 mg
$64.00
$341.00
0
(0)
Trapoxin A
Trapoxin A is a cyclotetrapeptide HDAC inhibitor
133155-89-2 sc-253730
1 mg
$165.00
0
(1)
Chidamide
Chidamide is an HDAC inhibitor
743420-02-2 sc-364462
sc-364462A
sc-364462B
1 mg
5 mg
25 mg
$60.00
$240.00
$1,150.00
0
(1)
LAQ824
LAQ824 is an HDAC inhibitor affecting p21
404951-53-7 sc-364521
sc-364521A
10 mg
50 mg
$225.00
$1,000.00
0
(0)
CUDC-101
CUDC-101 is a potent inhibitor to HDAC, EGFR and HER2
1012054-59-9 sc-364474
sc-364474A
10 mg
50 mg
$190.00
$700.00
0
(0)
AN-9
AN-9 is an HDAC inhibitor with antimetastic and antiangiogenic properties
122110-53-6 sc-364403
sc-364403A
5 mg
25 mg
$72.00
$269.00
0
(0)
PTACH
PTACH is a potent HDAC inhibitor
848354-66-5 sc-253326
2 mg
$216.00
0
(0)
Oxamflatin
Oxamflatin is a potent inhibitor of HDACs (histone deacetylases)
151720-43-3 sc-205960
sc-205960A
1 mg
5 mg
$80.00
$299.00
2
(1)
BML-210
BML-210 is an inhibitor of HDAC activity and gene expression modulator
537034-17-6 sc-221369
sc-221369A
1 mg
5 mg
$77.00
$263.00
0
(0)
ITF2357
ITF2357 is a potent inhibitor of HDAC with IC50 of 7.5-16 nM
732302-99-7 sc-364513
sc-364513A
5 mg
50 mg
$340.00
$1,950.00
0
(0)
Biphenyl-4-sulfonyl chloride
Biphenyl-4-sulfonyl chloride is a potent HDAC inhibitor with catalytic applications
1623-93-4 sc-254973
5 g
$55.00
0
(0)
HC Toxin
HC Toxin is an HDAC inhibitor
83209-65-8 sc-200884
1 mg
$152.00
1
(0)
SIRT1/2 Inhibitor VII
SIRT1/2 Inhibitor VII is an inhibitor of SIRT1/2 and HDAC
143034-06-4 sc-364618
10 mg
$113.00
0
(0)
(S)-HDAC-42
(S)-HDAC-42 is a potent inhibitor of HDAC
935881-37-1 sc-296364
sc-296364A
1 mg
5 mg
$86.00
$395.00
0
(0)
4-iodo-SAHA
4-iodo-SAHA is an HDAC1 and HDAC6 inhibitor
1219807-87-0 sc-364391
sc-364391A
50 mg
250 mg
$144.00
$650.00
0
(0)
L-Carnitine
L-Carnitine is a neuromodulator and antiaging agent
541-15-1 sc-205727
sc-205727A
sc-205727B
sc-205727C
1 g
5 g
100 g
250 g
$16.00
$25.00
$69.00
$166.00
0
(1)
Indole-3-acetamide
Indole-3-acetamide is a GSK-3β, VEGF, and JAK3 inhibitor
879-37-8 sc-255213
sc-255213A
1 g
5 g
$44.00
$198.00
0
(0)
Bufexamac
Bufexamac is a HDAC6 and HDAC10 inhibitor
2438-72-4 sc-227537
10 g
$75.00
0
(0)
NSC 3852
NSC 3852 is an inhibitor of HDAC (histone deacetylase)
3565-26-2 sc-205773
10 mg
$32.00
0
(1)
Ratjadone A, Synthetic
Ratjadone A, Synthetic is a cell-permeable polyketide that inhibits cell proliferation
163564-92-9 sc-203234
2 µg
$168.00
1
(0)
N-(2-Aminophenyl)-N'-phenylheptanediamide
N-(2-Aminophenyl)-N′-phenylheptanediamide is an HDAC inhibitor
537034-15-4 sc-207902
sc-207902A
10 mg
25 mg
$350.00
$810.00
1
(0)
APHA Compound 8
APHA Compound 8 is a synthetic HDAC (histone deacetylase) inhibitor
676599-90-9 sc-210828
1 mg
$84.00
0
(1)
Suberoylanilide-d5 Hydroxamic Acid
Suberoylanilide-d5 Hydroxamic Acid is a potent, selective, and cell permeable HDAC inhibitor
149647-78-9 (unlabeled) sc-220140
1 mg
$300.00
0
(0)
Dihydrochlamydocin
Dihydrochlamydocin is a biologically active peptide that acts as an HDAC inhibitor
sc-396552
250 µg
$90.00
0
(0)
7-Aminoindole
7-Aminoindole is a potent HDAC, PKC, and ARK inhibitor
5192-04-1 sc-257005
1 g
$555.00
0
(0)
HDAC Inhibitor XXIV
HDAC Inhibitor XXIV is an inhibitor of HDAC1, HDAC4, HDAC6, HDAC8, and HDAC11
sc-364505
10 mg
$225.00
0
(0)
Butyrylhydroxamic acid
Butyrylhydroxamic acid is a potent HDAC inhibitor
4312-91-8 sc-364450
sc-364450A
5 mg
25 mg
$65.00
$278.00
0
(0)
HNHA
HNHA is an HDAC (histone deacetylase) inhibitor
926908-04-5 sc-205343
sc-205343A
5 mg
10 mg
$161.00
$405.00
0
(0)
SB939
SB939 is a non-selective inhibitor of HDAC
929016-96-6 sc-364610
sc-364610A
5 mg
50 mg
$198.00
$815.00
0
(0)
BIX01294 hydrochloride
BIX01294 hydrochloride is a selective histone methyl transferase (HMTase) inhibitor.
1392399-03-9 sc-293525
sc-293525A
sc-293525B
1 mg
5 mg
25 mg
$35.00
$73.00
$294.00
0
(1)
MS-275
MS-275 is an HDAC inhibitor shown to inhibit angiogenesis and metastasis
209783-80-2 sc-279455
sc-279455A
sc-279455B
1 mg
5 mg
25 mg
$22.00
$86.00
$199.00
13
(2)
Valproic acid sodium salt
Valproic acid sodium salt is an HDAC inhibitor with anticancer, anti-inflammatory and neuroprotective effects
1069-66-5 sc-202378
5 g
$31.00
6
(1)
Tubacin
Tubacin is a selective inhibitor of HDAC6 that reversibly inhibits α-tubulin deacetylation
537049-40-4 sc-362815
sc-362815A
sc-362815B
sc-362815C
sc-362815D
1 mg
5 mg
50 mg
500 mg
1 g
$187.00
$415.00
$4,160.00
$10,330.00
$13,400.00
6
(1)
Trichostatin A
Trichostatin A is a potent and non-competitive reversible inhibitor of HDAC in LNCaP human prostate cancer cells, as well as in MON and HeLa cells.
58880-19-6 sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$137.00
$456.00
$600.00
$1,163.00
$2,000.00
22
(3)
Parthenolide
Parthenolide is an inhibitor specifically inhibits HDAC1 without affecting other class I/II HDACs
20554-84-1 sc-3523
sc-3523A
50 mg
250 mg
$72.00
$294.00
21
(2)
Sodium Butyrate
Sodium Butyrate is an HDAC inhibitor, apoptosis inducer and can induce differentiation and gene expression and also prevent cell proliferation
156-54-7 sc-202341
sc-202341B
sc-202341A
sc-202341C
250 mg
5 g
25 g
500 g
$20.00
$35.00
$70.00
$204.00
11
(2)
4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide
4-(dimethylamino)-N-[6-(hydroxyamino)-6-oxohexyl]-benzamide is a selective HDAC1 inhibitor
193551-00-7 sc-223859
sc-223859A
sc-223859B
sc-223859C
sc-223859D
1 mg
5 mg
10 mg
25 mg
60 mg
$32.00
$144.00
$257.00
$560.00
$1,200.00
0
(1)
HDAC6 Inhibitor
HDAC6 Inhibitor is an inhibitor of HDAC6
1045792-66-2 sc-223877
sc-223877A
500 µg
1 mg
$61.00
$84.00
3
(2)
Scriptaid
Scriptaid is an HDAC1, HDAC3, and HDAC8 inhibitor
287383-59-9 sc-202807
sc-202807A
1 mg
5 mg
$62.00
$175.00
7
(2)
M 344
M 344 is a potent HDAC inhibitor with IC50 of 100 nM
251456-60-7 sc-203124
sc-203124A
1 mg
5 mg
$99.00
$304.00
8
(1)
CBHA
CBHA is a potent HDAC inhibitor
174664-65-4 sc-205240
sc-205240A
5 mg
25 mg
$132.00
$395.00
2
(1)
CI 994
CI 994 is an HDAC1, HDAC3, HDAC6, and HDAC8 inhibitor
112522-64-2 sc-205245
sc-205245A
10 mg
50 mg
$97.00
$525.00
1
(2)
Splitomicin
Splitomicin is a Sir2p histone deactylease inhibitor
5690-03-9 sc-358701
5 mg
$46.00
0
(1)
Apicidin
Apicidin is an HDAC inhibitor and apoptosis inducer
183506-66-3 sc-202061
sc-202061A
1 mg
5 mg
$64.00
$194.00
8
(1)
Trichostatin C
Trichostatin C is an inducer of erythroid differentiation and histone H4 acetylation level
68676-88-0 sc-202369
500 µg
$359.00
2
(1)
Valproic Acid-d6
Valproic Acid-d6 is a deuterium-labelled form of Valproic Acid
87745-18-4 sc-213146
5 mg
$300.00
0
(0)
Butyric acid
Butyric acid is a histone deacetylase inhibitor
107-92-6 sc-214640
sc-214640A
1 kg
10 kg
$62.00
$171.00
0
(0)
2,2,3,3-Tetramethylcyclopropanecarboxylic acid
2,2,3,3-Tetramethylcyclopropanecarboxylic acid is used to start synthesis of central nervous system-active compounds
15641-58-4 sc-225566
1 g
$43.00
0
(0)
Pyroxamide
Pyroxamide is a HDAC1 inhibitor
382180-17-8 sc-397030
5 mg
$79.00
0
(0)
Panobinostat-d8 (Major) Hydrochloride Salt
Panobinostat-d8 (Major) Hydrochloride Salt is a novel labeled HDAC (histone deacetylase) inhibitor
404950-80-7 (unlabeled) sc-219552
sc-219552-CW
1 mg
1 mg
$210.00
$430.00
0
(0)
Isonipecotic acid
Isonipecotic acid is a HDAC inhibitor
498-94-2 sc-280859
100 g
$85.00
0
(0)
ATRA-BA Hybrid
ATRA-BA Hybrid is a differentiation inducer and HDAC inhibitor prodrug
sc-221275
25 mg
$340.00
0
(1)
MC 1293
MC 1293 is an inhibitor of HDAC1 and maize histone deacetylase HD2
sc-221875
5 mg
$173.00
1
(0)
Nullscript
Nullscript is a negative control for the HDAC inhibitor Scriptaid
300816-11-9 sc-222084
sc-222084A
1 mg
5 mg
$66.00
$258.00
0
(1)
Belinostat
Belinostat is a novel HDAC inhibitor
414864-00-9 sc-269851
sc-269851A
10 mg
100 mg
$150.00
$550.00
0
(1)
KD 5170
KD 5170 is an HDAC1, HDAC2, HDAC3, HDAC4, and HDAC6 inhibitor
940943-37-3 sc-362755
10 mg
$185.00
0
(0)
MC 1568
MC 1568 is a class II (IIa) HDAC inhibitor selective for HDAC4 and HDAC6
852475-26-4 sc-362767
sc-362767A
10 mg
50 mg
$175.00
$555.00
4
(1)
TC-H 106
TC-H 106 is a class I HDAC (histone deacetylase) inhibitor
937039-45-7 sc-362801
sc-362801A
10 mg
50 mg
$155.00
$620.00
0
(0)
1-Naphthohydroxamic Acid
1-Naphthohydroxamic Acid is a potent HDAC inhibitor with efficacy against HDAC8, HDAC1 and HDAC6
6953-61-3 sc-364388
sc-364388A
5 mg
25 mg
$65.00
$278.00
0
(0)
Droxinostat
Droxinostat is a selective inhibitor of HDAC3, HDAC6, and HDAC8
99873-43-5 sc-364485
sc-364485A
5 mg
25 mg
$85.00
$454.00
1
(0)
JNJ-26481585
JNJ-26481585 is an HDAC1, HDAC2, HDAC4, HDAC10, and HDAC11 inhibitor
875320-29-9 sc-364515
sc-364515A
5 mg
50 mg
$315.00
$1,200.00
0
(1)
Mocetinostat
Mocetinostat is a potent inhibitor of HDAC1, HDAC2, HDAC3, and HDAC11
726169-73-9 sc-364539
sc-364539B
sc-364539A
5 mg
10 mg
50 mg
$200.00
$230.00
$1,400.00
2
(1)
PCI-34051
PCI-34051 is a potent and specific HDAC8 inhibitor
950762-95-5 sc-364566
sc-364566A
10 mg
100 mg
$175.00
$1,600.00
2
(1)
Pimelic Diphenylamide 106
Pimelic Diphenylamide 106 is an HDAC1, HDAC2, HDAC3, and HDAC8 inhibitor
937039-45-7 sc-364589
sc-364589A
1 mg
5 mg
$41.00
$74.00
0
(0)
Romidepsin
Romidepsin is an HDAC1, HDAC2, HDAC4, and HDAC6 inhibitor
128517-07-7 sc-364603
sc-364603A
1 mg
5 mg
$568.00
$1,800.00
0
(1)
Tubastatin A (trifluoroacetate salt)
Tubastatin A (trifluoroacetate salt) is a neuroprotective HDAC6 and HDAC8 inhibitor
1239262-52-2 sc-364640
sc-364640A
sc-364640B
1 mg
5 mg
10 mg
$75.00
$225.00
$320.00
2
(1)
Tubastatin A hydrochloride
Tubastatin A hydrochloride is an HDAC6 inhibitor
1310693-92-5 sc-364641
sc-364641A
10 mg
50 mg
$180.00
$405.00
3
(0)

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