5-LO Inhibitors

Santa Cruz Biotechnology now offers a broad range of 5-LO Inhibitors. 5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes. 5-LO Inhibitors offered by Santa Cruz inhibit 5-LO and, in some cases, other leukotriene and lipid metabolite biosynthesis related proteins. View detailed 5-LO Inhibitor specifications, including 5-LO Inhibitor CAS number, molecular weight, molecular formula and chemical structure, by clicking on the product name.

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PRODUCT NAME/Application CAS Catalog # QUANTITY Price Citations RATING
U-73122
U-73122 is a phospholipase C,phospholipase A2, and 5-LO inhibitor
112648-68-7 sc-3574
sc-3574A
5 mg
25 mg
$116.00
$385.00
48
(2)
Esculetin
Esculetin is a hydroxyl radical and ROS scavenger that attenuates cellular oxidative stress
305-01-1 sc-200486
sc-200486A
1 g
5 g
$42.00
$204.00
6
(1)
Ketoconazole
Ketoconazole is an inhibitor of CYP proteins, thromboxane synthetase, and 5-LO
65277-42-1 sc-200496
sc-200496A
50 mg
500 mg
$54.00
$249.00
20
(1)
Curcumin (Synthetic)
Curcumin (Synthetic) is reported to suppress COX-1, COX-2, NF-κB and other inflammatory mediators
458-37-7 sc-294110
sc-294110A
5 g
25 g
$50.00
$150.00
3
(1)
Gossypol
Gossypol is an inhibitor of PKC, Bcl-2, 5-LO, and 12-LO
303-45-7 sc-200501
sc-200501A
20 mg
100 mg
$36.00
$107.00
11
(1)
N-Oleoyldopamine (OLDA)
N-Oleoyldopamine (OLDA) is a VR activator and 5-LO inhibitor
105955-11-1 sc-201456
sc-201456A
5 mg
25 mg
$74.00
$360.00
0
(0)
NDGA (Nordihydroguaiaretic acid)
NDGA (Nordihydroguaiaretic acid) is an antioxidant and lipoxygenase inhibitor
500-38-9 sc-200487
sc-200487A
sc-200487B
1 g
5 g
25 g
$80.00
$300.00
$1,485.00
3
(1)
Ebselen
Ebselen is a cysteine modifier that inhibits 5-LO, 15-LO, Cox, NADPH, and NADPH oxidase
60940-34-3 sc-200740B
sc-200740
sc-200740A
1 mg
25 mg
100 mg
$26.00
$125.00
$435.00
5
(1)
Ferulic acid
Ferulic acid is a chemopreventive analog of caffeic acid and inhibitor of 5-LO and 12-LO
1135-24-6 sc-204753
sc-204753A
sc-204753B
sc-204753C
sc-204753D
5 g
25 g
100 g
500 g
1 kg
$34.00
$54.00
$144.00
$535.00
$963.00
8
(3)
3-O-Acetyl-β-boswellic acid
3-O-Acetyl-β-boswellic acid is a non-competitive 5-lipoxygenase and topoisomerase I and IIa
5968-70-7 sc-202885
sc-202885A
1 mg
5 mg
$55.00
$123.00
0
(1)
Auranofin
Auranofin is a gold(I)-phosphine thiolate small molecule described to produce antiinflammatory and antiarthritic effects and an inhibitor of 5-LO (5-lipoxygenase)/LTA synthase
34031-32-8 sc-202476
sc-202476A
sc-202476B
25 mg
100 mg
2 g
$42.00
$76.00
$1,503.00
34
(1)
3,4-Dihydroxyphenyl Ethanol
3,4-Dihydroxyphenyl Ethanol is a phenolic antioxidant inhibitor of 5-LO (5-lipoxygenase) and 12-LO (12-lipoxygenase)
10597-60-1 sc-202887
10 mg
$80.00
6
(1)
Curcumin
Curcumin is a yellow-orange dye, NOS2 regulator, and inhibitor of NF-κB, 5-LO, Cox-2, COP9, and p300/CBP.
458-37-7 sc-200509
sc-200509A
sc-200509B
sc-200509C
sc-200509D
sc-200509F
sc-200509E
1 g
5 g
25 g
100 g
250 g
1 kg
2.5 kg
$19.00
$38.00
$60.00
$110.00
$220.00
$835.00
$1,920.00
38
(2)
Acetyl-11-keto-beta-Boswellic Acid, Boswellia serrata
Acetyl-11-keto-β-Boswellic Acid, Boswellia serrata is a 5-LO and topo I and II inhibitor
67416-61-9 sc-221208
5 mg
$164.00
0
(1)
ETYA
ETYA is a Cox, LO, and PLA2 inhibitor
1191-85-1 sc-200764
sc-200764A
20 mg
100 mg
$74.00
$307.00
2
(1)
Silybin
Silybin is a major active constituent of silymarin which inhibits mitogen-activated protein kinase (MAPK)
22888-70-6 sc-202812
sc-202812A
sc-202812B
sc-202812C
1 g
5 g
10 g
50 g
$30.00
$50.00
$96.00
$420.00
3
(1)
STEARDA
STEARDA is a 5-LO (5-lipoxygenase) inhibitor
105955-10-0 sc-204903
10 mg
$71.00
0
(0)
beta-Boswellic Acid
β-Boswellic Acid is an inhibitor of 5-LO and principal constituent of frankincense
631-69-6 sc-210958
5 mg
$300.00
1
(0)
Eicosapentaenoic Acid-d5
Eicosapentaenoic Acid-d5 is an ω-3 fatty acid abundantly available in marine organisms
1197205-73-4 sc-205304
sc-205304A
50 µg
500 µg
$104.00
$835.00
0
(0)
Meclofenamate sodium
Meclofenamate sodium is an inhibitor of 5-LO, Cox-1, and Cox-2
6385-02-0 sc-200532
sc-200532A
1 g
5 g
$50.00
$75.00
2
(0)
Zileuton Sulfoxide
Zileuton Sulfoxide is an orally active inhibitor of 5-lipoxygenase
1147524-83-1 sc-391271
5 mg
$300.00
1
(0)
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt
cis-5,8,11,14,17-Eicosapentaenoic acid sodium salt is an inhibitor of 5-LO
73167-03-0 sc-214735
sc-214735A
5 mg
25 mg
$47.00
$184.00
0
(0)
Caffeic Acid
Caffeic Acid is an inhibitor of 5-LO and 12-LO
331-39-5 sc-200499
sc-200499A
1 g
5 g
$30.00
$60.00
1
(2)
Baicalein
Baicalein is an inhibitor of Ca2+ uptake, 5-LO, and 12-LO
491-67-8 sc-200494
sc-200494A
10 mg
100 mg
$30.00
$40.00
11
(1)
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3)
Eicosa-5Z,8Z,11Z,14Z,17Z-pentaenoic Acid (20:5, n-3) is a 5-LO inhibitor
10417-94-4 sc-200766
sc-200766A
100 mg
1 g
$95.00
$410.00
0
(0)
ETI
ETI is a leukotriene antagonist and selective 5-LO (5-lipoxygenase) inhibitor
13488-22-7 sc-200762
sc-200762A
1 mg
10 mg
$83.00
$599.00
0
(0)
8,11,14-Eicosatriynoic Acid
8,11,14-Eicosatriynoic Acid is a Cox, 12-LO, and 5-LO inhibitor
34262-64-1 sc-221152
sc-221152A
1 mg
5 mg
$132.00
$595.00
0
(0)
5,6-dehydro Arachidonic Acid
5,6-dehydro Arachidonic Acid is a 5-LO inhibitor
58688-54-3 sc-205145
sc-205145A
25 µg
50 µg
$160.00
$304.00
0
(0)
RO 106-9920
RO 106-9920 is a NF-kB-dependent cytokine expression, 5-LO, and EGFR inhibitor
62645-28-7 sc-203240
sc-203240A
1 mg
5 mg
$135.00
$575.00
6
(1)
SKF 86002
SKF 86002 is an inhibitor of p53, Cox, and 5-LO
72873-74-6 sc-203265
5 mg
$153.00
0
(0)
Piriprost (potassium salt)
Piriprost (potassium salt) is a structural analog of prostaglandin I2
88851-62-1 sc-205440
sc-205440A
1 mg
5 mg
$82.00
$370.00
0
(0)
7,7-Dimethyleicosadienoic Acid (DEDA)
7,7-Dimethyleicosadienoic Acid (DEDA) is an inhibitor of PLA2, sPLA2, and 5-LO
89560-01-0 sc-200707
sc-200707A
10 mg
50 mg
$95.00
$350.00
0
(0)
BW A4C
BW A4C is a selective 5-LO (5-lipoxygenase) inhibitor
106328-57-8 sc-210981
sc-210981A
5 mg
25 mg
$137.00
$660.00
0
(0)
Zileuton
Zileuton is a 5-LO (5-lipoxygenase) inhibitor
111406-87-2 sc-204417
sc-204417A
sc-204417B
sc-204417C
10 mg
50 mg
1 g
75 g
$56.00
$168.00
$350.00
$1,200.00
6
(1)
2-TEDC
2-TEDC is a 5-LO, 12-LO, and 15-LO inhibitor
132465-10-2 sc-203772
sc-203772A
10 mg
50 mg
$125.00
$525.00
1
(0)
CDC
CDC is an inhibitor of 5-LO, 12-LO, and 15-LO
132465-11-3 sc-200562
sc-200562A
10 mg
50 mg
$75.00
$309.00
0
(1)
BW B70C
BW B70C is a 5-LO (5-lipoxygenase) inhibitor
134470-38-5 sc-200633
sc-200633B
sc-200633A
sc-200633C
sc-200633D
sc-200633E
5 mg
10 mg
25 mg
50 mg
100 mg
250 mg
$83.00
$166.00
$592.00
$739.00
$1,200.00
$2,000.00
0
(1)
Licofelone
Licofelone is an inhibitor of Cox-1, Cox-2, and 5-lipoxygenase, that causes little or no gastric mucosa damage in rabbit parietal cells.
156897-06-2 sc-207826
sc-207826A
sc-207826B
sc-207826C
5 mg
250 mg
1 g
4 g
$60.00
$240.00
$800.00
$3,200.00
4
(1)
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole
3-[[3-fluoro-5-(tetrahydro-4-methoxy-2H-pyran-4-yl)phenoxy]methyl]-1-[4-(methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole is a dual inhibitor of Cox-2 and 5-LO
443919-96-8 sc-205108
sc-205108A
1 mg
5 mg
$90.00
$406.00
0
(0)
15(S)-HETrE
15(S)-HETrE is a 5-LO (5-lipoxygenase) inhibitor
92693-02-2 sc-205043
sc-205043A
25 µg
50 µg
$120.00
$200.00
0
(0)
15(S)-HETE-biotin
15(S)-HETE-biotin is an inhibitor of 5-LO (5-lipoxygenase)
sc-220636
sc-220636A
25 µg
50 µg
$237.00
$341.00
0
(0)
(+/-) 5-HETE Lactone
(±) 5-HETE Lactone is an inhibitor and marker of 5-LO activity
73279-37-5 sc-200957
sc-200957A
50 µg
1 mg
$101.00
$1,140.00
0
(0)
Butyrolactone II
Butyrolactone II is an antibiotic, a 5-LOX inhibitor and has shown DPPH radical-scavening activity
87414-44-6 sc-396570
500 µg
$195.00
0
(0)
15(S)-HEDE
15(S)-HEDE is a 5-LO (5-lipoxygenase) inhibitor
92693-04-4 sc-220635
50 µg
$349.00
0
(0)
YS121
YS121 is an inhibitor of mPGES-1, 5-LO, Cox-1, and Cox-2
916482-17-2 sc-296707
sc-296707A
1 mg
5 mg
$56.00
$251.00
0
(0)
ZLJ-6
ZLJ-6 is an inhibitor of Cox-1, Cox-2, and 5-LO
1051931-39-5 sc-224468
sc-224468A
1 mg
5 mg
$40.00
$180.00
0
(0)
CAY10589
CAY10589 is an inhibitor of 5-LO, Cox-1, and Cox-2
1077626-52-8 sc-223872
sc-223872A
1 mg
5 mg
$56.00
$255.00
0
(0)