Date published: 2026-1-22

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4E-BP Antibodies

Santa Cruz Biotechnology features a diverse variety of 4E-BP monoclonal antibodies for studying eukaryotic translation initiation factor 4E-binding proteins. Multiple research applications are supported, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). 4E-BP proteins regulate protein synthesis by binding to the translation initiation factor eIF4E, which inhibits cap-dependent translation. This regulation influences cellular processes including growth, proliferation, and stress response mechanisms. Understanding 4E-BP protein function has significant implications for cancer research and diseases linked to abnormal protein synthesis. Researchers can investigate translation regulation pathways through detailed molecular analysis. Advanced detection methods enable precise visualization and quantification of 4E-BP expression patterns. Experimental approaches using specific molecular markers help reveal regulatory networks in both normal and disease states. Santa Cruz Biotechnology monoclonal antibodies support scientific advancement by enabling researchers to uncover new insights into translation control mechanisms and their impact on human health.

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4E-BP Antibodies

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4E-BP1 Antibody (P-1)

sc-9977mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h and porcine
42
(36)

4E-BP1 Antibody (11G12C11)

sc-81149mouse IgG1 κ1-118 (h)WB, IP, IF, IHC(P)m, r, h
16
(9)

4E-BP1 Antibody (D-10)

sc-514073mouse IgG2a κ2-25 (h)WB, IP, IF, IHC(P), ELISAm, r, h
3
(3)

4E-BP3 Antibody (4-RY9)

sc-134232mouse IgG2a κ1-101 (h)WB, IP, ELISAh
2
(2)

Phospho-Specific 4E-BP Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-4E-BP1 Antibody (62.Ser 65)

sc-293124mouse IgG2b κSer 65 (h)WB, IP, ELISAm, r, h
33
(19)

p-4E-BP1/2/3 Antibody (A-10)

sc-271947mouse IgG2a κThr 45 (h)WB, IP, IF, ELISAm, r, h
7
(9)

4E-BP CRISPR Knockout, HDR and Double Nickase Plasmids

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4E-BP1 CRISPR/Cas9 KO Plasmid (h2)

sc-400398-KO-2hGene KnockoutGFP0
(0)

4E-BP1 HDR Plasmid (h2)

sc-400398-HDR-2hHomology Directed RepairPuromycin0
(0)

4E-BP1 Double Nickase Plasmid (h)

sc-400398-NIChGene KnockoutPuromycin0
(0)

4E-BP1 Double Nickase Plasmid (h2)

sc-400398-NIC-2hGene KnockoutPuromycin0
(0)

4E-BP1 CRISPR/Cas9 KO Plasmid (m)

sc-420149mGene KnockoutGFP0
(0)

4E-BP2 CRISPR/Cas9 KO Plasmid (h)

sc-410771hGene KnockoutGFP0
(0)

4E-BP2 HDR Plasmid (h)

sc-410771-HDRhHomology Directed RepairPuromycin0
(0)

4E-BP2 CRISPR/Cas9 KO Plasmid (m)

sc-420150mGene KnockoutGFP0
(0)

4E-BP3 CRISPR/Cas9 KO Plasmid (h2)

sc-406304-KO-2hGene KnockoutGFP0
(0)

4E-BP3 HDR Plasmid (h2)

sc-406304-HDR-2hHomology Directed RepairPuromycin0
(0)

4E-BP CRISPR Activation Products

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4E-BP1 CRISPR Activation Plasmid (h)

sc-400398-ACThGene ActivationPuro, Blast, Hygro0
(0)

4E-BP1 CRISPR Activation Plasmid (h2)

sc-400398-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

4E-BP1 CRISPR Activation Plasmid (m)

sc-420149-ACTmGene ActivationPuro, Blast, Hygro0
(0)

4E-BP1 Lentiviral Activation Particles (m)

sc-420149-LACmGene ActivationPuro, Blast, Hygro0
(0)

4E-BP siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

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4E-BP1 siRNA (h)

sc-29594hGene SilencingN/A
12
(0)

4E-BP1 shRNA Plasmid (h)

sc-29594-SHhGene SilencingPuromycin
12
(0)

4E-BP1 shRNA (h) Lentiviral Particles

sc-29594-VhGene SilencingPuromycin
12
(0)

4E-BP1 siRNA (m)

sc-29595mGene SilencingN/A
2
(0)

4E-BP1 shRNA Plasmid (m)

sc-29595-SHmGene SilencingPuromycin
2
(0)

4E-BP1 shRNA (m) Lentiviral Particles

sc-29595-VmGene SilencingPuromycin
2
(0)

4E-BP2 siRNA (h)

sc-77246hGene SilencingN/A0
(0)

4E-BP2 shRNA Plasmid (h)

sc-77246-SHhGene SilencingPuromycin0
(0)

4E-BP2 shRNA (h) Lentiviral Particles

sc-77246-VhGene SilencingPuromycin0
(0)

4E-BP2 siRNA (m)

sc-77247mGene SilencingN/A0
(0)

4E-BP2 shRNA Plasmid (m)

sc-77247-SHmGene SilencingPuromycin0
(0)

4E-BP2 shRNA (m) Lentiviral Particles

sc-77247-VmGene SilencingPuromycin0
(0)

4E-BP3 siRNA (h)

sc-91863hGene SilencingN/A0
(0)

4E-BP3 shRNA Plasmid (h)

sc-91863-SHhGene SilencingPuromycin0
(0)

4E-BP3 shRNA (h) Lentiviral Particles

sc-91863-VhGene SilencingPuromycin0
(0)