Chemicals classified as Ankfn1 Inhibitors encompass a range of compounds that can indirectly impact the function of Ankfn1 through modulation of various cellular signaling pathways and processes. These compounds target enzymes, receptors, and signaling molecules that are upstream or downstream of the processes Ankfn1 is thought to be involved with. The table includes compounds like Cyclosporin A, which through inhibition of calcineurin, can affect T-cell activation where Ankfn1 may play a role. Compounds such as Curcumin and DAPT can affect NF-κB and Notch signaling pathways, respectively, thus potentially altering the cellular environment and the context within which Ankfn1 operates.
Furthermore, small molecule inhibitors like PD173074 and SB431542 target growth factor receptors and signaling molecules, which can indirectly influence Ankfn1's role in growth and differentiation. Y-27632 and Blebbistatin interfere with cytoskeletal dynamics and myosin II activity, respectively, which may impact the structural context of Ankfn1's function. The inclusion of inhibitors like LY294002 and ZM 336372 reflects the potential alteration of survival and proliferative signaling pathways, such as PI3K/Akt and MAPK/ERK, which could impact Ankfn1's regulatory role. U73122 and XAV939 target phospholipase C and tankyrase, affecting calcium signaling and Wnt/β-catenin pathways, further showcasing the diversity of cellular processes that these inhibitors can influence, and hence potentially modulate the functional capacity of Ankfn1.
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Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
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Cyclosporin A | 59865-13-3 | sc-3503 sc-3503-CW sc-3503A sc-3503B sc-3503C sc-3503D | 100 mg 100 mg 500 mg 10 g 25 g 100 g | $62.00 $90.00 $299.00 $475.00 $1015.00 $2099.00 | 69 | |
An immunosuppressant that can inhibit calcineurin, therefore affecting NFAT signaling, which can alter Ankfn1's potential role in T-cell activation. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $36.00 $68.00 $107.00 $214.00 $234.00 $862.00 $1968.00 | 47 | |
A compound that can modulate NF-κB activity, potentially influencing Ankfn1's role in inflammatory signaling pathways. | ||||||
PD173074 | 219580-11-7 | sc-202610 sc-202610A sc-202610B | 1 mg 5 mg 50 mg | $46.00 $140.00 $680.00 | 16 | |
An FGFR inhibitor that can affect fibroblast growth factor signaling, potentially influencing Ankfn1's role in cellular growth and development. | ||||||
SB 431542 | 301836-41-9 | sc-204265 sc-204265A sc-204265B | 1 mg 10 mg 25 mg | $80.00 $212.00 $408.00 | 48 | |
An inhibitor of TGF-β type I receptor ALK5, which can affect TGF-β signaling, potentially altering Ankfn1's involvement in cellular differentiation. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
A Rho-associated protein kinase inhibitor that can affect cytoskeleton organization, potentially impacting Ankfn1's role in cellular structure. | ||||||
(S)-(−)-Blebbistatin | 856925-71-8 | sc-204253 sc-204253A sc-204253B sc-204253C | 1 mg 5 mg 10 mg 25 mg | $71.00 $260.00 $485.00 $949.00 | ||
An inhibitor of myosin II ATPase activity, which can prevent proper cytoskeleton function, potentially affecting Ankfn1's role in cellular mechanics. | ||||||
CCG-1423 | 285986-88-1 | sc-205241 sc-205241A | 1 mg 5 mg | $30.00 $90.00 | 8 | |
A RhoA transcriptional signaling inhibitor that can affect cytoskeleton organization and cell motility, potentially influencing Ankfn1's role. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
A PI3K inhibitor that can modulate the PI3K/Akt pathway, potentially altering Ankfn1's involvement in cellular survival and metabolism. | ||||||
ZM 336372 | 208260-29-1 | sc-202857 | 1 mg | $46.00 | 2 | |
A RAF-1 inhibitor that can affect the MAPK/ERK pathway, potentially influencing Ankfn1's role in cell proliferation and differentiation. | ||||||
DAPT | 208255-80-5 | sc-201315 sc-201315A sc-201315B sc-201315C | 5 mg 25 mg 100 mg 1 g | $99.00 $335.00 $836.00 $2099.00 | 47 | |
A γ-secretase inhibitor, which can affect Notch signaling, potentially altering Ankfn1's role in cell fate decisions. |