2200001I15Rik Inhibitors
The chemical class referred to as 2200001I15Rik Inhibitors comprises a diverse array of compounds targeting key signaling pathways and cellular processes associated with the protein encoded by gene 2200001I15Rik. These inhibitors act on various levels, disrupting crucial molecular events that influence the protein's function. BAY 11-7082, for instance, hinders NF-κB activation, impeding the nuclear translocation of the protein. SP600125 and SB203580 selectively target JNK and p38 MAP kinase, respectively, influencing downstream cascades linked to 2200001I15Rik. LY294002 and Wortmannin, as PI3K inhibitors, modulate signaling pathways pivotal for the protein's activity.
Moreover, U0126 and PD98059, both MEK inhibitors, disrupt the MAPK/ERK pathway, which may impact the function of 2200001I15Rik. AG490, targeting JAK, and S3I-201, inhibiting STAT3 dimerization, interfere with critical signaling events that may involve the protein. SP2509 and C646, affecting BRD4 and HAT, respectively, modulate chromatin structure and gene expression patterns, potentially influencing 2200001I15Rik. Additionally, AUY922, a HSP90 inhibitor, can lead to the degradation of client proteins associated with the function of 2200001I15Rik. This chemical class showcases a strategic approach to inhibit the protein by targeting diverse molecular players within the intricate network of cellular signaling pathways.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
BAY 11-7082 | 19542-67-7 | sc-200615B sc-200615 sc-200615A | 5 mg 10 mg 50 mg | $61.00 $83.00 $349.00 | 155 | |
BAY 11-7082 is an inhibitor of NF-κB activation. It disrupts the interaction between IκBα kinase and NF-κB, preventing the translocation of NF-κB to the nucleus, ultimately inhibiting 2200001I15Rik. | ||||||
SP600125 | 129-56-6 | sc-200635 sc-200635A | 10 mg 50 mg | $40.00 $150.00 | 257 | |
SP600125 is a potent and selective inhibitor of c-Jun N-terminal kinase (JNK), a kinase involved in various cellular processes. Inhibiting JNK can impact downstream signaling cascades associated with 2200001I15Rik. | ||||||
SB 203580 | 152121-47-6 | sc-3533 sc-3533A | 1 mg 5 mg | $88.00 $342.00 | 284 | |
SB203580 is a specific inhibitor of p38 MAP kinase. By blocking p38 activation, it interferes with pathways linked to the protein encoded by gene 2200001I15Rik, potentially hindering its function. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $121.00 $392.00 | 148 | |
LY294002 is a phosphoinositide 3-kinase (PI3K) inhibitor. Disrupting PI3K signaling can influence downstream pathways, possibly affecting the function of 2200001I15Rik. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $66.00 $219.00 $417.00 | 97 | |
Wortmannin is another PI3K inhibitor that can modulate signaling cascades. Its interference with PI3K-dependent pathways might impact the activity of the protein encoded by gene 2200001I15Rik. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $63.00 $241.00 | 136 | |
U0126 is a selective inhibitor of MEK1 and MEK2, key components of the MAPK/ERK pathway. Blocking this pathway may disrupt signaling events associated with the protein coded by 2200001I15Rik. | ||||||
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
PD98059 is a compound that specifically inhibits MEK1, affecting the MAPK/ERK pathway. Interfering with this pathway can potentially influence the function of the protein encoded by gene 2200001I15Rik. | ||||||
AG-490 | 133550-30-8 | sc-202046C sc-202046A sc-202046B sc-202046 | 5 mg 50 mg 25 mg 10 mg | $82.00 $323.00 $219.00 $85.00 | 35 | |
AG490 is a Janus kinase (JAK) inhibitor. By blocking JAK activity, it can disrupt downstream signaling pathways, potentially impacting the function of the protein coded by 2200001I15Rik. | ||||||
SP2509 | 1423715-09-6 | sc-492604 | 5 mg | $284.00 | ||
SP2509 is a selective inhibitor of bromodomain-containing protein 4 (BRD4). Inhibition of BRD4 can modulate chromatin structure, influencing gene expression, including genes related to 2200001I15Rik. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $260.00 $925.00 | 5 | |
C646 is a histone acetyltransferase (HAT) inhibitor, targeting p300/CBP-associated factor (PCAF). Modulating histone acetylation can affect gene expression patterns, potentially influencing 2200001I15Rik. | ||||||